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Advanced Musculoskeletal Magnetic Resonance Imaging at Ultra-high Field (7 T)

  • Siegfried Trattnig
  • Klaus Friedrich
  • Wolfgang Bogner
  • Klaus Scheffler
  • Oliver Bieri
  • Goetz H. Welsch
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

The major advantage of high-field and ultra-high field MR is the shift from morphological to biochemical and metabolic imaging techniques which normally suffer from low sensitivity at standard field strength (1.5 T). The high signal-to-noise ratio of the higher field systems provides biochemical and metabolic imaging in reasonable scan times, which promotes their widespread clinical application. This development enables the diagnosis of diseases such as osteoarthritis, degenerative disc disease, and muscle disease at their earliest stages, before morphological changes occur. Thus, the imaging pre-requisites are available for the evaluation and follow-up of new disease-modifying drugs and the trend toward more personalized medicine.

Keywords

Articular Cartilage Specific Absorption Rate Turbo Spin Echo Sequence Fixed Charge Density Cartilage Repair Tissue 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

MR

Magnetic resonance

SNR

Signal-to-noise ratio

SAR

Specific absorption rate

TSE

Turbo Spin Echo

HASTE

Half-Fourier acquisition single-shot turbo spin echo

TrueFISP

True Fast Imaging with Steady-state Free Precession

RF

Radiofrequency

MRI

Magnetic resonance imaging

μMRI

Microscopy magnetic resonance imaging

OA

Osteoarthiritis

UTE

Ultrashort echo time

NYUMC

New York University Langone Medical Center

TFCC

Triangular fibrocartilage complex

PG

Proteoglycan

GAG

Glycosaminoglycans

FCD

Fixed charge density

TQF

Triple-quantum filtered

TPI

Twisted projection imaging

SQ

Single-quantum

dGEMRIC

Delayed gadolinium enhanced MRI of cartilage

MACT

Matrix-associated autologous transplantation

3D GRE

Three dimensional gradient echo

IR

Inversion recovery

IVD

Intervertebral discs

AF

Annulus fibrosus

NP

Nucleus pulposus

B0

Main magnetic field

TR

Repetition time

SE T2

Spin-echo T2 relaxation time constant

31P-MRS

Phosporus MR spectroscopy

1H-MRS

Hydrogen MR spectroscopy

CSA

Chemical shift anisotropy

ATP

Adenosine triphosphate

PME

Phosphomonoesters

PDE

Phosphodiester

CSDE

Chemical shift displacement error

3D-CSI

Three dimensional Chemical Shift Imaging

PCr

Phosphocreatine

ADP

Adenosine diphosphate

PC

Phosphocholine

PE

Phosphoethanolamine

Pi

Inorganic phosphate

GPC

Glycophosphocholine

Spsp

Spectral-spatial

FATSAT

Fat saturation

MTC

Magnetization transfer contrast

CW

Continuous wave

SSFP

Steady-state free precession

DESS

Double-echo steady state

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Copyright information

© Springer-Verlag Berlin Heidelberg 2012

Authors and Affiliations

  • Siegfried Trattnig
    • 1
  • Klaus Friedrich
    • 1
  • Wolfgang Bogner
    • 1
  • Klaus Scheffler
    • 2
  • Oliver Bieri
    • 2
  • Goetz H. Welsch
    • 1
    • 3
  1. 1.Department of Radiology, High-Field MR Imaging CentreMedical University of ViennaViennaAustria
  2. 2.Division of Radiological Physics, Department of Medical RadiologyUniversity of Basel HospitalBaselSwitzerland
  3. 3.Department of Trauma SurgeryUniversity Hospital of ErlangenErlangenGermany

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