Breast Cancer

Part of the Medical Radiology book series (MEDRAD)


Locally recurrent breast cancer occurs in 5–15% of patients after breast conservation therapy and after mastectomy with adjuvant radiotherapy. Ipsilateral breast recurrences may be salvaged with mastectomy, however, outcomes from repeat breast conserving surgery and breast re-irradiation is promising. Chest wall recurrence generally portends a worse prognosis than in-breast local recurrences. A subset of patients may be long-term survivors in the absence of metastasis. Persistent chest wall disease can be symptomatic, and in previously irradiated patients, treatment options are limited. Experiences with chest wall re-irradiation have shown excellent response rates with acceptable late toxicity, but follow-up is limited.


Chest Wall Planning Target Volume Complete Response Rate Breast Conservation Surgery Accelerate Partial Breast Irradiation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of Radiation OncologyUniversity of Nebraska Medical Center, Eppley Cancer CenterOmahaUSA
  2. 2.Department of Radiation OncologyThe Robert H. Lurie Comprehensive Cancer Center of Northwestern UniversityChicagoUSA

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