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Soft Tissue Sarcomas

  • Daniel J. Indelicato
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

The incidence of local recurrence after wide local excision and radiation of soft tissue sarcoma (STS) ranges from 5 to 20%. Approximately 80% of these relapses will occur in the absence of metastatic disease. The optimal management of locally recurrent STS must be individualized and depends on prior therapy, the location of the recurrence, and the feasibility of conservative surgery. Following retreatment, the likelihood of ultimate local control ranges from 37 to 100% and is a reflection of well-known risk factors for de novo sarcomas such as the number of prior recurrences, high grade, positive margins, deep location, and non-extremity tumor site. Approaches for retreatment include wide local reexcision followed by a variety of radiation techniques, each with the potential for severe side effects. For select patients, repeat irradiation may be unnecessary.

Keywords

Soft Tissue Sarcoma Wide Local Excision Intraarterial Chemotherapy Brachytherapy Boost Recurrent Sarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of Radiation OncologyUniversity of Florida College of MedicineGainesvilleUSA
  2. 2.University of Florida Proton Therapy InstituteJacksonvilleUSA

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