Brain Tumors

  • Jennifer E. Gains
  • Susan C. Short
Part of the Medical Radiology book series (MEDRAD)


Historically radiation oncologists have been cautious about re-irradiating brain tumours because of concerns about the risks of late central nervous system toxicity, especially radionecrosis, which may occur several months to years after treatment. There is, however, a lack of prospective data addressing this approach. Re-irradiation of brain tumours is attracting more interest as our understanding of the tolerance of the brain to radiation evolves, and developments in radiation technology and imaging make highly accurate targeting of biologically relevant tumour volumes possible. With developments in molecular-targeted therapy, further exploration of the role of re-irradiation on its own or in combination with novel agents is needed.


High Grade Glioma Stereotactic Radiotherapy Recursive Partitioning Analysis Recurrent Glioma Target Definition 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.University College HospitalLondonUK
  2. 2.UCL Cancer InstituteLondonUK

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