Pulmonary Nodules and Lung Cancer

  • Thomas Henzler
  • Gerald Schmid-Bindert
  • Christian Fink
Part of the Medical Radiology book series (MEDRAD)


Worldwide, lung cancer is the leading cause of cancer mortality in men and women. The therapeutic options for lung cancer have been substantially improved. Sophisticated surgical techniques have increased the number of patients considered as being technically resectable. On the other hand, multimodal treatment strategies using induction chemotherapy or radiotherapy have increased the number of patients finally undergoing surgical resection. But even in inoperable patients, new chemotherapeutic agents or targeted therapies have improved the survival of patients with lung cancer. As a consequence, the demands for diagnostic radiology in patients with lung cancer have changed. The differentiation of iodinated contrast media by DECT is a potential surrogate marker for regional blood volume and thus angiogenesis, which has already been used for non-invasive characterization of pulmonary nodules. Future studies have to evaluate further potential applications of DECT in lung cancer staging and response evaluation.


Vascular Endothelial Growth Factor Expression Pulmonary Nodule Malignant Nodule Benign Nodule High Vascular Endothelial Growth Factor Expression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Thomas Henzler
    • 1
  • Gerald Schmid-Bindert
    • 2
  • Christian Fink
    • 1
  1. 1.Department of Clinical Radiology and Nuclear MedicineUniversity Medical Center Mannheim, Medical Faculty Mannheim of the University of HeidelbergMannheimGermany
  2. 2.Interdisciplinary Thoracic OncologyUniversity Medical Center Mannheim, Medical Faculty Mannheim of the University of HeidelbergMannheimGermany

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