The Case for MDCT

  • Carlo Nicola De Cecco
  • Franco Iafrate
  • Marco Rengo
  • Saif Ramman
  • Andrea Laghi
Part of the Medical Radiology book series (MEDRAD)


Multidetector CT (MDCT) examination with multiphasic acquisition should be advocated as routine study in patient investigated for pancreatic adenocarcinoma. The application of a biphasic protocol gives the best results, using a pancreatic phase for tumor identification and arterial infiltration, and portal phase for the assement of venous infiltration and liver metastasis. Pancreatic adenocarcinoma is classically visualized as an ill-defined solid mass, not capsulated, isodense to the pancreatic parenchyma in pre-contrast scan and hypo-attenuating in the pancreatic-portal phases. Ancillary signs can be helpful in the diagnosis of small tumors (< 2 cm) and isoattenuating adenocarcinoma. Several benign and malignant condition can mimick adenocarcinoma, in this case magnetic resonance and endoscopic ultrasonography biopsy can be helpful in diagnosis. MDCT enables an accurate tumor staging and presents a positive predictive values for unresectability between 89% to 100%; it also allows a complete preoperative planning and presents high accuracy both in surgical complications and tumor recurrence detection.


Acute Pancreatitis Chronic Pancreatitis Pancreatic Adenocarcinoma Superior Mesenteric Vein Bile Duct Stone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Carlo Nicola De Cecco
    • 1
    • 2
  • Franco Iafrate
    • 1
  • Marco Rengo
    • 1
  • Saif Ramman
    • 3
  • Andrea Laghi
    • 1
  1. 1.Department of Radiological SciencesUniversity of Rome “Sapienza” – Polo PontinoLatinaItaly
  2. 2.Department of Radiological SciencesUniversity of Rome “Sapienza” – St. Andrea HospitalRomeItaly
  3. 3.University of GlasgowGlasgowUK

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