Fetal MRI pp 329-341 | Cite as

Diagnosis of Congenital Diaphragmatic Hernia

  • Mieke Cannie
  • Jacques Jani
Part of the Medical Radiology book series (MEDRAD)


With advances in ultrasound technology, congenital diaphragmatic hernia (CDH) is easily diagnosed prenatally. In contrast, prenatal prognostication remains a challenge. In view of the current availability of fetal therapy this becomes even more important. To date, one of the most studied markers is the lung-area to head circumference ratio and has been shown in large studied to be predictive of postnatal outcome in terms of survival and also morbidity. Since the fetal lung is a fluid filled structure hence has high signal intensity on T2-WI, it can be easily discernible from the surrounding structures using fetal magnetic resonance imaging (MRI). This remains so even in case of oligohydramnios and obesity, conditions that make appropriate ultrasound evaluation difficult and inaccurate. The advantage of prenatal assessment in CDH using fetal MRI is that both lungs can be measured accurately, prediction can be adjusted to fetal biometry using the fetal body volume and intrathoracic position of the liver can be quantified, given a more accurate prediction of postnatal survival rather than the simple semiquantitative assessment of liver position. Further research using fetal MRI is directed towards the assessment of lungs at the microstructural level.


Apparent Diffusion Coefficient Congenital Diaphragmatic Hernia Congenital Diaphragmatic Hernia Pulmonary Hypoplasia Contralateral Lung 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  1. 1.Department of RadiologyUniversity Hospital BrugmannBrusselsBelgium
  2. 2.Departments of Radiology, UZ BrusselsVrije Universiteit BrusselsBrusselsBelgium
  3. 3.Department of Obstetrics and Gynaecology, Section Fetal Medicine and TherapyUniversity Hospital BrugmannBrusselsBelgium

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