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Fetal MRI pp 287-308 | Cite as

Cerebral Malformations

  • Daniela Prayer
  • Peter C. Brugger
  • Ursula Nemec
  • Ruxandra Iulia Milos
  • Christian Mitter
  • Gregor Kasprian
Chapter
Part of the Medical Radiology book series (MEDRAD)

Abstract

During the second trimester cerebral malformations may present with morphological features that are different from those that are seen in a more mature brain. Consequently, the chapter focuses on early detection of cerebral malformations. MR- sequences that might be useful for the detection of changes in fetal brain development are described. A schematic approach, including the assessment of lamination of the brain parenchyma, the appearance of deep gray matter structures, the width and shape of the ventricles and outer CSF spaces, the midline structures, and the cerebellum is suggested. Salient features of the second-trimester appearance of lissencephaly/polymicrogyria syndromes, holoprosencephaly (HPE), and commissural agenesis that may be detected early are discussed.

Keywords

Fourth Ventricle Gestational Week Septum Pellucidum Cerebellar Hypoplasia Cavum Septi Pellucidi 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer-Verlag Berlin Heidelberg 2010

Authors and Affiliations

  • Daniela Prayer
    • 1
  • Peter C. Brugger
    • 2
  • Ursula Nemec
    • 1
  • Ruxandra Iulia Milos
    • 1
  • Christian Mitter
    • 1
  • Gregor Kasprian
    • 1
  1. 1.Division of Neuroradiology and Musculokeletal Radiology, Department of RadiologyMedical University ViennaViennaAustria
  2. 2.Center of Anatomy and Cell BiologyMedical University of ViennaViennaAustria

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