Miscellaneous Conditions with Manifestations in the Hand and Wrist

  • Vikram S. Sandhu
  • A. Mark DaviesEmail author
  • Steven L. James
Part of the Medical Radiology book series (MEDRAD)


In any textbook dealing with conditions affecting a particular anatomical site, there will be some which do not fit conveniently under the standard chapter headings. The purpose of this chapter is to review these miscellaneous localised and systemic disorders that may affect the hand and wrist.


Carpal Tunnel Syndrome Complex Regional Pain Syndrome Reflex Sympathetic Dystrophy Tubular Bone Pyrophosphate Dihydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. Ahlberg AK (1975) On the natural history of hemophilic pseudotumor. J Bone Joint Surg Am 57A:1133–1136Google Scholar
  2. Al-Boukai AA, Hawass NE, Patel PJ, Kolawole TM (1989) Camel bites: report of severe osteolysis as late bone complications. Postgrad Med J 65:900–904PubMedCrossRefGoogle Scholar
  3. Ali A, Tetalman MR, Fordham EW et al (1980) Distribution of hypertrophic pulmonary osteoarthropathy. AJR Am J Roentgenol 134:771–780PubMedCrossRefGoogle Scholar
  4. Bernauer TA, Mirowski GW, Caldemeyer KS (2001) Tuberous sclerosis: II. Musculoskeletal and visceral findings. J Am Acad Dermatol 45:450–452PubMedCrossRefGoogle Scholar
  5. Bohrer SP (1970) Acute long bone diaphyseal infarcts in sickle cell disease. Br J Radiol 43:685–697PubMedCrossRefGoogle Scholar
  6. Boutin RD, Spitz DJ, Newman JS, Lenchik L, Steinbach LS (1998) Complications in Paget disease at MR imaging. Radiology 209:641–651PubMedGoogle Scholar
  7. Brudin L, Valind S, Rhodes C et al (1994) Fluorine-18 deoxyglucose uptake in sarcoidosis measured with positron emission tomography. Eur J Nucl Med 21:297–305PubMedCrossRefGoogle Scholar
  8. Caffey J (1951) Chronic poisoning due to excess vitamin A. AJR Am J Roentgenol 65:12–26Google Scholar
  9. Caffey J (1957) Cooley’s anemia: a review of the roentgenographic findings in the skeleton. Hickey Lecture. AJR Am J Roentgenol 78:381–391Google Scholar
  10. Calif E, Vlodavsky E, Stahl S (2007) Ivory fingers: monostotic Paget’s disease of the phalanges. J Clin Endocrinol Metabolism 92:1590–1591CrossRefGoogle Scholar
  11. Christie DP (1980) The spectrum of radiographic bone changes in children with fluorosis. Radiology 136:85–90PubMedGoogle Scholar
  12. Cobby MJ, Adler RS, Swartz R, Martel W (1991) Dialysis-related amyloid arthropathy: MR findings in four patients. AJR Am J Roentgenol 157:1023–1027PubMedCrossRefGoogle Scholar
  13. Cockshott WP (1963) Dactylitis and growth disorders. Br J Radiol 36:19–26PubMedCrossRefGoogle Scholar
  14. Cundy T (2006) Is Paget’s disease of bone disappearing. Skeletal Radiol 35:350–351PubMedCrossRefGoogle Scholar
  15. Davies AM, Colley SP, James SLJ, Sumathi VP, Grimer RJ (2010) Erdheim–Chester disease presenting with destruction of a metacarpal. Clin Radiol 65:250–253PubMedCrossRefGoogle Scholar
  16. De Smet AA, Kuhns LR, Fayos JV, Holt JF (1976) Effects of radiation therapy on growing long bones. AJR Am J Roentgenol 127:935–939PubMedCrossRefGoogle Scholar
  17. De Smet L, Roosen P, Zachee B et al (1994) Monostotic localization of Paget disease in the hand. Acta Orthop Belg 60:184–186PubMedGoogle Scholar
  18. De Wind LT (1961) Hypervitaminosis D with osteosclerosis. Arch Dis Child 36:373–380CrossRefGoogle Scholar
  19. Dearbon GV (1932) A case of congenital general pure analgesia. J Nerv Ment Dis 75:612CrossRefGoogle Scholar
  20. Destouet JM, Murphy WA (1981) Guitar player acro-osteolysis. Skeletal Radiol 6:275–277PubMedCrossRefGoogle Scholar
  21. Friedman A, Orcutt J, Madewell J (1982) Paget disease of the hand: radiographic spectrum. Am J Roentgenol 138(4):691–693CrossRefGoogle Scholar
  22. Gama C, Meira JB (1978) Occupational acro-osteolysis. J Bone Joint Surg Am 60A:86–90Google Scholar
  23. Gibson MS, Jennings BT, Murphey MD (2008) Hypertrophic osteoarthropathy. In: Pope TL Jr, Bloem HL, Beltran J, Morrison WB, Wilson DJ (eds) Imaging of the musculoskeletal system, vol 2. Saunders Elsevier, Philadelphia, p 1612Google Scholar
  24. Gorham LW, Stout AP (1955) Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone): its relation to haemangiomatosis. J Bone Joint Surg Am 37A:985–1004Google Scholar
  25. Gwathmey FW, House JH (1984) Clinical manifestations of congenital insensitivity of the hand and classification of syndromes. J Hand Surg [Am] 9A:863–869Google Scholar
  26. Hall-Edwards J (1908) The effects upon bone due to prolonged exposure to X-rays. Arch Roentgen Ray 13:44Google Scholar
  27. Hartwell SW Jr, Huger W Jr, Pickrell K (1964) Radiation dermatitis and radiogenic neoplasms of the hands. Ann Surg 160:828–834PubMedCrossRefGoogle Scholar
  28. Haverbush T, Wilde A, Phalen G (1972) The hand in Paget’s disease of bone: report of two cases. J Bone Joint Surg Am 54A:173–175Google Scholar
  29. Hildebrandt JW, Olson P, Paratainen H, Griffiths H (1993) Macrodystrophia lipomatosa. Orthopedics 16:1075–1077PubMedGoogle Scholar
  30. Huang TT, Blackwell SJ, Lewis SR (1978) Hand deformities in patients with snake bite. Plast Reconstr Surg 62:32–36PubMedCrossRefGoogle Scholar
  31. Karmani S, Shedden R, De Sousa C (2001) Orthopaedic manifestations of congenital insensitivity to pain. J R Soc Med 94:139–140PubMedGoogle Scholar
  32. Katzman BM, Caligiuri DA, Klein DM, Perrier G, Dauterman PA (1997) Sarcoid flexor tenosynovitis of the wrist: a case report. J Hand Surg Am 22:336–337PubMedCrossRefGoogle Scholar
  33. Kaufmann GA, Sundaram M, McDonald DJ (1991) MR imaging in symptomatic Paget’s disease. Skeletal Radiol 20:413–418PubMedCrossRefGoogle Scholar
  34. Kiss E, Keusch G, Zanetti M, Jung T, Schwarz A, Schocke M, Jaschke W, Czermak BV (2005) Dialysis-related amyloidosis revisited. AJR Am J Roentgenol 185:1460–1470PubMedCrossRefGoogle Scholar
  35. Lanzer W, Szabo R, Gelberman R (1984) Avascular necrosis of the lunate and sickle cell anemia: a case report. Clin Orthop Relat Res 187:168–171PubMedGoogle Scholar
  36. Leone AJ Jr (1968) On lead lines. AJR Am J Roentgenol 103:165–167CrossRefGoogle Scholar
  37. Libshitz HI, Cohen MA (1982) Radiation-induced osteochondromas. Radiology 142:643–647PubMedGoogle Scholar
  38. Lopez C, Thomas DV, Davies AM (2003) Neoplastic transformation and tumour-like lesions in Paget’s disease of bone: a pictorial review. Eur Radiol 13:L151–L163PubMedCrossRefGoogle Scholar
  39. Love C, Tomas M, Tronco G et al (2005) FDG PET of infection and inflammation. Radiographics 25:1357–1368PubMedCrossRefGoogle Scholar
  40. Marie P (1890) De l’osteoarthropathie hypertrophiante pneumonique. Rev Med (Paris) 10:1–36Google Scholar
  41. Middlemiss JH, Raper AB (1966) Skeletal changes in the haemoglobinopathies. J Bone Joint Surg Br 48B:693–701Google Scholar
  42. Moore S (2003) Musculoskeletal sarcoidosis: spectrum of appearances at MR imaging. Radiographics 23:1389–1399PubMedCrossRefGoogle Scholar
  43. Neville E, Carstairs LS, James DG (1976) Bone sarcoidosis. Ann N Y Acad Sci 278:475–487PubMedCrossRefGoogle Scholar
  44. Neville EW, Carstairs LS, James DG (1977) Sarcoidosis of bone. Q J Med 46:215–217PubMedGoogle Scholar
  45. Park JS, Ryu KN (2004) Hemophilic pseudotumor involving the musculoskeletal system: spectrum of radiologic findings. AJR Am J Roentgenol 183:55–61PubMedCrossRefGoogle Scholar
  46. Park SA, Yang CY, Shin YI, Oh GJ, Lee M (2009) Patterns of three-phase bone scintigraphy according to the time course of complex regional pain syndrome type 1 after a stroke or traumatic brain injury. Clin Nucl Med 34:773–776PubMedCrossRefGoogle Scholar
  47. Patel DV (2005) Gorham’s disease or massive osteolysis. Clin Med Res 3:65–74PubMedCrossRefGoogle Scholar
  48. Pineda CJ, Martinez-Lavin M, Goodbar JE et al (1987) Periostitis in hypertrophic osteoarthropathy: relationship to disease duration. AJR Am J Roentgenol 148:773–778PubMedCrossRefGoogle Scholar
  49. Qteishat WA, Whitehouse GH, Hawass N (1985) Acro-osteolysis following snake and scorpion envenomisation. Br J Radiol 58:1035–1039PubMedCrossRefGoogle Scholar
  50. Rahalkar MD, Rahalkar AM, Joshi SK (2008) Case series: congenital insensitivity to pain and anhidrosis. Indian J Radiol Imaging 18:132–134CrossRefGoogle Scholar
  51. Ranawat CS, Arora MM, Singh RG (1968) Macrodystrophia lipomatosa with carpal tunnel syndrome: a case report. J Bone Joint Surg Am 50A:1242–1244Google Scholar
  52. Reilly MM (2009) Classification and diagnosis of inherited neuropathies. Ann Indian Acad Neurol 12:80–88PubMedCrossRefGoogle Scholar
  53. Resnick D (2002) Osteolysis and chondrolysis. In: Resnick D (ed) Diagnosis of bone and joint disorders, 4th edn. WB Saunders Co., Philadelphia, pp 4920–4944Google Scholar
  54. Resnick D, Pineda CJ, Weisman HM, Kerr R (1985) Osteomyelitis and septic arthritis of the hand following human bites. Skeletal Radiol 14:263–266PubMedCrossRefGoogle Scholar
  55. Rodriguez-Peralto J, Ro J, McCabe K et al (1994) Case report 806: monostotic Paget’s disease of the hand. Skeletal Radiol 23:55–57PubMedGoogle Scholar
  56. Sachs H (1981) The evolution of the radiologic lead line. Radiology 139:81–85PubMedGoogle Scholar
  57. Schumacher HR Jr (1964) Hemochromotosis and arthritis. Arthritis Rheum 7:41–50PubMedCrossRefGoogle Scholar
  58. Shaheen S, Alasha E (2005) Hemophilic pseudotumor of the distal parts of the radius and ulna: a case report. J Bone Joint Surg Am 87A:2546–2549CrossRefGoogle Scholar
  59. Shaw JA, Wilson SC (1993) Multiple hemophilic bone cysts in the hand. J Hand Surg Am 18:262–264PubMedCrossRefGoogle Scholar
  60. Siegelman SS, Heimann WG, Manin MC (1966) Congenital indifference to pain. AJR Am J Roentgenol 97:242–247CrossRefGoogle Scholar
  61. Silverman FN, Gilden JJ (1959) Congenital insensitivity to pain: a neurologic syndrome with bizarre skeletal lesions. Radiology 72:176–190PubMedGoogle Scholar
  62. Smith S, Murphey M, Motamedi K et al (2002) Radiologic spectrum of Paget’s disease of bone and its complications with pathologic correlation. Radiographics 22:1191–1216PubMedGoogle Scholar
  63. Sundaram M, Khanna G, El-Khoury GY (2001) T1-weighteds MR imaging for distinguishing large osteolysis of Paget’s disease from sarcomatous degeneration. Skeletal Radiol 30:378–383PubMedCrossRefGoogle Scholar
  64. Van Linthoudt D, Ott H (1986) An unusual case of sarcoid dactylitis. Br J Rheumatol 25:222–224PubMedCrossRefGoogle Scholar
  65. Vande Berg B, Malghem J, Lecouvet F et al (2001) Magnetic resonance appearance of uncomplicated Paget’s disease of bone. Semin Musculoskelet Radiol 1:69–77CrossRefGoogle Scholar
  66. Warady BA, Haug SJ, Lindsley CB (1991) Multicentric osteolysis: an infrequently recognized renal-rheumatologic syndrome. J Rheumatol 18:142–145PubMedGoogle Scholar
  67. Watson RJ, Burko H, Megas H, Robinson M (1963) The hand–foot syndrome in sickle cell disease in young children. Pediatrics 31:975–982PubMedGoogle Scholar
  68. Westermark P, Benson MD, Buxbaum JN et al (2002) Amyloid fibril protein nomenclature. Amyloid J Protein Folding Disord 9:197–200CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2013

Authors and Affiliations

  • Vikram S. Sandhu
    • 1
  • A. Mark Davies
    • 2
    Email author
  • Steven L. James
    • 2
  1. 1.Imaging DepartmentRoyal Orthopaedic HospitalBirminghamUK
  2. 2.Department of RadiologyRoyal Orthopaedic HospitalBirminghamUK

Personalised recommendations