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Re-irradiation: New Frontiers pp 171–182Cite as

Gynaecological Malignancies

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Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Gynaecological cancer patients who present with an isolated recurrence after having undergone definitive radiation treatment pose a therapeutic dilemma, balancing risks of retreatment with a desire to optimise local control. A patient’s suitability for a radical approach to retreatment is determined by multiple factors: their clinical performance status and symptomatology, previous radiotherapy and radiation-related toxicities and disease extent. Ever improving technologies have changed the goalposts for treatment, and an aggressive approach is worth pursuing in carefully selected patients, where not only palliation of local symptoms is possible but also long-term local control can be a realistic aim. In this review, clinical, tumour and radiobiological factors as well as technological features have been formulated into a treatment algorithm for the patient presenting for consideration of re-irradiation for recurrent gynaecological malignancy.

M. Morgia and L. Walsh contributed equally to this work.

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Authors and Affiliations

  1. Department of Radiation Oncology, Princess Margaret Hospital, University of Toronto, Toronto, Canada

    M. Morgia, L. Walsh, M. Milosevic, W. Levin & A. Fyles

Authors
  1. M. Morgia
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  2. L. Walsh
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  3. M. Milosevic
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  4. W. Levin
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  5. A. Fyles
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Corresponding author

Correspondence to A. Fyles .

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Editors and Affiliations

  1. , Dept. Internal Medicine, Nordlandssykehuset HF, Prinsensgate 164, Bodoe, 8092, Norway

    Carsten Nieder

  2. Department of Radiation Oncology, University Medical Center Groningen, Hanzeplein 1, Groningen, 9700 RB, Netherlands

    Johannes A. Langendijk

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© 2010 Springer-Verlag Berlin Heidelberg

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Morgia, M., Walsh, L., Milosevic, M., Levin, W., Fyles, A. (2010). Gynaecological Malignancies. In: Nieder, C., Langendijk, J. (eds) Re-irradiation: New Frontiers. Medical Radiology(). Springer, Berlin, Heidelberg. https://doi.org/10.1007/174_2010_106

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  • DOI: https://doi.org/10.1007/174_2010_106

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  • Print ISBN: 978-3-642-12467-9

  • Online ISBN: 978-3-642-12468-6

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