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Allergy and Cancer: New Perspectives

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Cancer Research: An Interdisciplinary Approach

Abstract

Allergy prevalence, immune system hypersensitivity, is increasing worldwide. There are evidences supporting the association between allergies and cancers. Immune surveillance hypotheses and antigenic stimulation theory are two main contradictory hypotheses about this linkage. Most of the studies support a negative association between allergy history and the risk of acute and chronic leukemia, esophageal cancer, stomach cancer, melanoma and non-melanoma skin cancer, cervical cancer, pancreatic cancer, and brain malignant tumors like glioma. Furthermore, there are evidences of a positive relationship between atopy and the risk of lung cancer and SCC. About the other types of cancer, the results were inconclusive. In this chapter, we will review the possible mechanisms involved in causing this association, and we will review evidences about the correlation between allergies and cancers of different organs.

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Jamshidi, P., Mosavari, N., Najafi, D., Siri, M.A., Samieefar, N., Rezaei, N. (2022). Allergy and Cancer: New Perspectives. In: Rezaei, N. (eds) Cancer Research: An Interdisciplinary Approach. Interdisciplinary Cancer Research, vol 1. Springer, Cham. https://doi.org/10.1007/16833_2022_1

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