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Factors Maximizing Skin Flaps and Grafts for Diabetic Wound Coverage

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  • First Online:
Pressure Injury, Diabetes and Negative Pressure Wound Therapy

Part of the book series: Recent Clinical Techniques, Results, and Research in Wounds ((RCTRRW,volume 3))

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Abstract

Diabetes mellitus has a global impact and accounts for 46% of the 162,000 hospital admissions for foot ulcers annually. The pathophysiological mechanisms underlying diabetic foot disease are multifactorial and include neuropathy, infection, immunopathy, and ischemia. The author discusses general reconstruction, general principles for success in flaps and grafts, optimizing of patients, biomechanics, immune system, vascular disease and reperfusion, physiologic considerations in flap perfusion, intraoperative care and flap technique, tissue management (biofilm, bacteria, inflammation), various flaps, and nonsurgical management. Accurate diagnosis of the underlying cause of lower extremity ulceration is essential for successful treatment.

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Authors and Affiliations

  1. Podiatry Care, P.C., Enfield, CT, USA

    Ryan Donegan D.P.M., M.S.

  2. Section of Podiatric Surgery, Department of Orthopedics and Rehabilitation, Yale New Haven Hospital, New Haven, CT, USA

    Ryan Donegan D.P.M., M.S.

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    Melvin A. Shiffman

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    Mervin Low

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Donegan, R. (2018). Factors Maximizing Skin Flaps and Grafts for Diabetic Wound Coverage. In: Shiffman, M., Low, M. (eds) Pressure Injury, Diabetes and Negative Pressure Wound Therapy. Recent Clinical Techniques, Results, and Research in Wounds, vol 3. Springer, Cham. https://doi.org/10.1007/15695_2017_48

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