Abstract
One-pot multistep reactions based on thiolactone chemistry have emerged as a powerful tool for modifying thiolactone-containing polymers in one-pot and in an elegant manner. In general, thiolactones can be opened by a wide variety of functional amines and the released thiol can react with thiol ‘scavengers’ of choice. This overview highlights the most important features of this approach, illustrated by the versatile and site-specific double post-polymerization modification of various reactive systems.
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Acknowledgements
Both authors are thankful to Ghent University, the Belgian program on Interuniversity Attraction Poles initiated by the Belgian State, the Prime Minister’s office (P7/05), and the European Science Foundation Precision Polymer Materials (P2M) program for financial support.
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Espeel, P., Du Prez, F.E. (2014). One-Pot Double Modification of Polymers Based on Thiolactone Chemistry. In: Theato, P. (eds) Multi-Component and Sequential Reactions in Polymer Synthesis. Advances in Polymer Science, vol 269. Springer, Cham. https://doi.org/10.1007/12_2014_304
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