Abstract
Polymeric bionanocomposites (PBNCs) have established themselves as a promising class of hybrid materials derived from natural and synthetic biodegradable polymers and organic/inorganic fillers. A critical factor underlying biomedical nanocomposite properties is the interaction between the chosen matrix and the filler. This chapter discusses current efforts and key research challenges in the development of these composite materials for use in potential drug delivery applications. PBNCs discussed here include layered PBNCs, quantum-dot-loaded PBNCs, clay-dispersed PBNCs, carbon-nanotube-loaded PBNCs, core–shell PBNCs, hydrogel-based PBNCs, and magnetic PBNCs. We conclude that PBNCs are promising materials for drug delivery applications.
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Acknowledgments
One of the authors, R. Jayakumar, is grateful to SERC Division, Department of Science and Technology (DST), India, for providing the fund under the scheme of “Fast Track Scheme for Young Investigators” (Ref. No. SR/FT/CS-005/2008). The authors are thankful to Department of Biotechnology (DBT), Government of India for providing financial support to carry out research work under the Bioengineering Program (Ref. No. BT/PR13885/MED/32/145/2010).
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Prabaharan, M., Jayakumar, R. (2011). Polymeric Bionanocomposites as Promising Materials for Controlled Drug Delivery. In: Jayakumar, R., Prabaharan, M., Muzzarelli, R. (eds) Chitosan for Biomaterials II. Advances in Polymer Science, vol 244. Springer, Berlin, Heidelberg. https://doi.org/10.1007/12_2011_111
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DOI: https://doi.org/10.1007/12_2011_111
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