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Enzymatic Synthesis of Polyesters via Polycondensation

  • Hiroshi Uyama
  • Shiro KobayashiEmail author
Chapter
Part of the Advances in Polymer Science book series (POLYMER, volume 194)

Abstract

In vitro synthesis of polyesters by polycondensation using isolated enzymes as catalyst via nonbiosynthetic pathways is reviewed. In most cases, lipase was used as catalyst and the polyesters were obtained from oxyacids, their esters, and dicarboxylic acid derivatives/glycols. Enzymatic polymerization proceeded under mild reaction conditions in comparison with chemical processes. By utilizing characteristic properties of lipases, regio- and enantioselective polymerizations proceeded to give functional polymers, most of which are difficult to synthesize by conventional methodologies.

Enzyme Lipase Polyester Polycondensation Biodegradable polymer 

Abbreviations

BOD

biochemical oxygen demand

DP

degree of polymerization

ee

enantiomeric excess

Lipase A

Aspergillus niger lipase

Lipase CA

Candida antarctica lipase

Lipase CR

Candida rugosa lipase

Lipase MM

Mucor miehei lipase

Lipase PC

Pseudomonas cepacia lipase

Lipase PF

Pseudomonas fluorescens lipase

PEG

poly(ethylene glycol)

PHA

poly(hydroxyalkanoate)

PHB

poly(3-hydroxybutyrate)

PPL

porcine pancreas lipase

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Authors and Affiliations

  1. 1.Department of Materials Chemistry, Graduate School of EngineeringOsaka UniversitySuitaJapan
  2. 2.Department of Materials Chemistry, Graduate School of EngineeringKyoto UniversityKyotoJapan

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