Hydrogen Atom Donors: Recent Developments

  • Andreas GansäuerEmail author
  • Lei Shi
  • Matthias Otte
  • Inga Huth
  • Antonio Rosales
  • Iris Sancho-Sanz
  • Natalia M. Padial
  • J. Enrique OltraEmail author
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 320)


This review highlights recent developments in the field of hydrogen atom transfer (HAT) reagents that circumvent the disadvantages of classical group 14 reagents, such as Bu3SnH. Special emphasis is laid on the lowering of bond dissociation energies (BDEs) of molecules that could, as yet, not be used as HAT reagents and on the use of organometallic HAT reagents.

Graphical abstract


Bond dissociation energies Catalysis Chain reactions Hydrogen atom transfer Metal-hydrogen bonds Radicals 





Bond dissociation energy


Catalytic hydrogen atom transfer










Hydrogen atom transfer


N-Heterocyclic carbene





We are grateful for continued financial support by the Deutsche Forschungsgemeinschaft, the Alexander von Humboldt-Stiftung, and the Fonds der Chemischen Industrie. We also thank the Spanish Ministry of Science and Innovation and the Regional Government of Andalucía for projects CTQ2008-06790/BQU and P07-FQM-03213 and aids to the PAI group FQM-339.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2011

Authors and Affiliations

  • Andreas Gansäuer
    • 1
    Email author
  • Lei Shi
    • 1
  • Matthias Otte
    • 1
  • Inga Huth
    • 1
  • Antonio Rosales
    • 2
  • Iris Sancho-Sanz
    • 2
  • Natalia M. Padial
    • 2
  • J. Enrique Oltra
    • 2
    Email author
  1. 1.Kekulé Institut für Organische Chemie und Biochemie der Universität BonnBonnGermany
  2. 2.Department of Organic Chemistry, Faculty of SciencesUniversity of GranadaGranadaSpain

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