The Class Imbalance Problem in TLC Image Classification

  • António V. Sousa
  • Ana Maria Mendonça
  • Aurélio Campilho
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4142)


The paper presents the methodology developed to solve the class imbalanced problem that occurs in the classification of Thin-Layer Chromatography (TLC) images. The proposed methodology is based on re-sampling, and consists in the undersampling of the majority class (normal class), while the minority classes, which contain Lysosomal Storage Disorders (LSD) samples, are oversampled with the generation of synthetic samples. For image classification two approaches are presented, one based on a hierarchical classifier and another uses a multiclassifier system, where both classifiers are trained and tested using balanced data sets. The results demonstrate a better performance of the multiclassifier system using the balanced sets.


Minority Class Synthetic Sample Lysosomal Storage Disorder Class Imbalance Class Imbalance Problem 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • António V. Sousa
    • 1
    • 2
  • Ana Maria Mendonça
    • 2
    • 3
  • Aurélio Campilho
    • 2
    • 3
  1. 1.Instituto Superior de Engenharia do PortoPortoPortugal
  2. 2.Instituto de Engenharia BiomédicaPortoPortugal
  3. 3.Faculdade de Engenharia da Universidade do PortoPortoPortugal

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