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CFD Analysis Incorporating the Influence of Wall Motion: Application to Intracranial Aneurysms

  • Laura Dempere-Marco
  • Estanislao Oubel
  • Marcelo Castro
  • Christopher Putman
  • Alejandro Frangi
  • Juan Cebral
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4191)

Abstract

Haemodynamics, and in particular wall shear stress, is thought to play a critical role in the progression and rupture of intracranial aneurysms. A novel method is presented that combines image-based wall motion estimation obtained through non-rigid registration with computational fluid dynamics (CFD) simulations in order to provide realistic intra-aneurysmal flow patterns and understand the effects of deforming walls on the haemodynamic patterns. In contrast to previous approaches, which assume rigid walls or ad hoc elastic parameters to perform the CFD simulations, wall compliance has been included in this study through the imposition of measured wall motions. This circumvents the difficulties in estimating personalized elasticity properties. Although variations in the aneurysmal haemodynamics were observed when incorporating the wall motion, the overall characteristics of the wall shear stress distribution do not seem to change considerably. Further experiments with more cases will be required to establish the clinical significance of the observed variations.

Keywords

Computational Fluid Dynamic Wall Motion Wall Shear Stress Intracranial Aneurysm Computational Fluid Dynamic Simulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Laura Dempere-Marco
    • 1
  • Estanislao Oubel
    • 1
  • Marcelo Castro
    • 2
  • Christopher Putman
    • 3
  • Alejandro Frangi
    • 1
  • Juan Cebral
    • 2
  1. 1.Department of TechnologyPompeu Fabra UniversityBarcelonaSpain
  2. 2.School of Computational SciencesGeorge Mason UniversityFairfaxUSA
  3. 3.Interventional NeuroradiologyInova Fairfax HospitalFalls ChurchUSA

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