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Physiome Model Based State-Space Framework for Cardiac Kinematics Recovery

  • Ken C. L. Wong
  • Heye Zhang
  • Huafeng Liu
  • Pengcheng Shi
Part of the Lecture Notes in Computer Science book series (LNCS, volume 4190)

Abstract

In order to more reliably recover cardiac information from noise-corrupted patient-specific measurements, it is essential to employ meaningful a priori constraining models and adopt appropriate optimization criteria to couple the models with the measurements. While biomechanical models have been extensively used for myocardial motion recovery with encouraging results, the passive nature of such constraints limits their ability to fully count for the deformation caused by active forces of the myocytes. To overcome such limitations, we propose to adopt a cardiac physiome model as the prior constraint for heart motion analysis. The model is comprised of a cardiac electric wave propagation model, an electromechanical coupling model, and a biomechanical model, and thus more completely describes the macroscopic cardiac physiology. Embedded within a multiframe state-space framework, the uncertainties of the model and the patient-specific measurements are systematically dealt with to arrive at optimal estimates of the cardiac kinematics and possibly beyond. Experiments have been conducted on synthetic data and MR image sequences to illustrate its abilities and benefits.

Keywords

Synthetic Data Active Force Biomechanical Model Active Region Model Iterative Close Point Algorithm 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2006

Authors and Affiliations

  • Ken C. L. Wong
    • 1
  • Heye Zhang
    • 1
  • Huafeng Liu
    • 3
  • Pengcheng Shi
    • 1
    • 2
  1. 1.Department of Electronic and Computer EngineeringHong Kong University of Science and TechnologyHong Kong
  2. 2.School of Biomedical EngineeringSouthern Medical UniversityGuangzhouChina
  3. 3.State Key Laboratory of Modern Optical InstrumentationZhejiang UniversityHanzhouChina

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