CT and PET Registration Using Deformations Incorporating Tumor-Based Constraints

  • Antonio Moreno
  • Gaspar Delso
  • Oscar Camara
  • Isabelle Bloch
Part of the Lecture Notes in Computer Science book series (LNCS, volume 3773)


Registration of CT and PET thoracic images has to cope with deformations of the lungs during breathing. Possible tumors in the lungs usually do not follow the same deformations, and this should be taken into account in the registration procedure. We show in this paper how to introduce tumor-based constraints into a non-linear registration of thoracic CT and PET images. Tumors are segmented by means of a semi-automatic procedure and they are used to guarantee relevant deformations near the pathology. Results on synthetic and real data demonstrate a significant improvement of the combination of anatomical and functional images for diagnosis and for oncology applications.


Positron Emission Tomography Compute Tomography Image Positron Emission Tomography Image Source Image Target Image 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2005

Authors and Affiliations

  • Antonio Moreno
    • 1
    • 2
  • Gaspar Delso
    • 3
  • Oscar Camara
    • 4
  • Isabelle Bloch
    • 1
  1. 1.Ecole Nationale Supérieure des TélécommunicationsTSI Department, CNRS UMR 5141ParisFrance
  2. 2.SegamiParisFrance
  3. 3.Philips Medical SystemsSuresnesFrance
  4. 4.Center for Medical Image Computing, Department of Medical PhysicsUniversity College LondonLondonUK

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