Abstract
We present a biophysical model of saccade initiation based on competitive integration of planned and reactive cortical saccade decision signals in the intermediate layer of the superior colliculus. In the model, the variable slopes of the climbing activities of the input cortical decision signals are produced from variability in the conductances of Na + , K + , Ca2 + activated K + , NMDA and GABA currents. These cortical decision signals are integrated in the activities of buildup neurons in the intermediate layer of the superior colliculus, whose activities grow nonlinearly towards a preset criterion level. When the level is crossed, a movement is initiated. The resultant model reproduces the unimodal distributions of saccade reaction times (SRTs) for correct antisaccades and erroneous prosaccades as well as the variability of SRTs (ranging from 80ms to 600ms) and the overall 25% of erroneous prosaccade responses in a large sample of 2006 young men performing an antisaccade task.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Durstewitz, D.: Self Organizing Neural Integrator Predicts Interval Times Through Climbing Activity. J. Neurosci. 23(12), 5342–5353 (2003)
Shampine, L.F., Reichelt, M.W.: The MATLAB ODE Suite. SIAM Journal on Scientific Computing 18, 1–22 (1997)
Evdokimidis, I., Smyrnis, N., Constantinidis, T.S., Stefanis, N.C., Avramopoulos, D., Paximadis, C., Theleritis, C., Efstratiadis, C., Kastrinakis, G., Stefanis, C.N.: The Antisaccade Task in a Sample of 2006 Young Men I. Normal Population Characteristics. Exp. Brain Res. 147, 45–52 (2002)
Hallett, P.R.: Primary and Secondary Saccades to Goals Defined by Instructions. Vis. Res. 18, 1279–1296 (1978)
Hanes, D.P., Schall, J.D.: Neural Control of Voluntary Movement Initiation. Science 274, 427–430 (1996)
Reddi, B.A.J., Carpenter, R.H.S.: The Influence of Urgency on Decision Time. Nat. Neurosci. 3, 827–831 (2000)
Smyrnis, N., Evdokimidis, I., Stefanis, N.C., Constantinidis, T.S., Avramopoulos, D., Theleritis, C., Paximadis, C., Efstratiadis, C., Kastrinakis, G., Stefanis, C.N.: The Antisaccade Task in a Sample of 2006 Young Males II. Effects of Task Parameters. Exp. Brain Res. 147, 53–63 (2002)
Everling, S., Dorris, M.C., Klein, R.M., Munoz, D.P.: Role of Primate Superior Colliculus in Preparation and Execution of Anti-saccades and Prosaccades. J. Neurosci. 19(7), 2740–2754 (1998)
Cutsuridis, V., Smyrnis, N., Evdokimidis, I., Perantonis, S.: A Neural Model of Decision Making by the Superior Colliculus in an Antisaccade Task. Submitted to Biol. Cybernetics
Durstewitz, D., Seamans, J.K., Sejnowski, T.J.: Dopamine-Mediated Stabilization of Delay-Period Activity in a Network Model of Prefrontal Cortex. J. Neurophys. 83, 1733–1750 (2000)
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer-Verlag Berlin Heidelberg
About this paper
Cite this paper
Cutsuridis, V., Kahramanoglou, I., Perantonis, S., Evdokimidis, I., Smyrnis, N. (2005). A Biophysical Model of Decision Making in an Antisaccade Task Through Variable Climbing Activity. In: Duch, W., Kacprzyk, J., Oja, E., Zadrożny, S. (eds) Artificial Neural Networks: Biological Inspirations – ICANN 2005. ICANN 2005. Lecture Notes in Computer Science, vol 3696. Springer, Berlin, Heidelberg. https://doi.org/10.1007/11550822_33
Download citation
DOI: https://doi.org/10.1007/11550822_33
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-540-28752-0
Online ISBN: 978-3-540-28754-4
eBook Packages: Computer ScienceComputer Science (R0)