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Aptamer-Modified Nanoparticles in Medical Applications

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Aptamers in Biotechnology

Part of the book series: Advances in Biochemical Engineering/Biotechnology ((ABE,volume 174))

Abstract

Since aptamers have been selected against a broad range of target structures of medical interest and nanoparticles are available with diverse properties, aptamer-modified nanoparticles can be used in various diagnostic and therapeutic applications. While the aptamer is responsible for specificity and affinity of the conjugate, the nanoparticles’ function varies from signal generation in diagnostic approaches to drug loading in drug delivery systems. Within this chapter different medical applications of aptamer-modified nanoparticles will be summarized and underlying principles will be described.

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Acknowledgments

This work was funded by the Ministry of Science and Culture of Lower Saxony (MWK Niedersachsen).

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  1. Alina Eilers and Sandra Witt contributed equally to this work.

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  1. Institut für Technische Chemie, Hannover, Germany

    Alina Eilers, Sandra Witt & Johanna Walter

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  1. Alina Eilers
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  2. Sandra Witt
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Correspondence to Johanna Walter .

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  1. Basel, Switzerland

    Katharina Urmann

  2. University Hannover, Gottfried-Wilhelm Leibniz, Hannover, Niedersachsen, Germany

    Johanna-Gabriela Walter

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Eilers, A., Witt, S., Walter, J. (2020). Aptamer-Modified Nanoparticles in Medical Applications. In: Urmann, K., Walter, JG. (eds) Aptamers in Biotechnology. Advances in Biochemical Engineering/Biotechnology, vol 174. Springer, Cham. https://doi.org/10.1007/10_2020_124

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