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Nano/Micro Biotechnology pp 231–250Cite as

Sensors

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Part of the book series: Advances in Biochemical Engineering / Biotechnology ((ABE,volume 119))

Abstract

With recent advances in nanotechnology, development of nanomaterial bioconjugates is growing exponentially towards eventual translation into biomolecular recognition layers on surfaces. Label-free monitoring of biorecognition events is also key-technology and provides a promising platform, which is simple, cost-effective, and requires no external modification to biomolecules. In this review, we describe the application of nanomaterials, mainly metal nanoparticles, and specific applications of carbon nanotubes (CNTs) based label-free approaches.

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Abbreviations

µTAS:

Micro total analysis system

Aβ:

Amyloid-beta

AFB1:

Aflatoxin B1

AFM:

Atomic force microscope

CNTFETs:

Carbon nanotube field-effect transistors

CNTs:

Carbon nanotubes

DMPC:

Dimyristoylphosphatidylcholine

DPV:

Differential pulse voltammetry

FET:

Field-effect transistor

GOxGOD:

Glucose oxidase

HBM:

Hybrid bilayer membrane

hCG:

Human chorionic gonadotropin hormone

HRP:

Horseradish peroxidase

IgE:

Immunoglobulin E

LOD:

Limit of detection

MWCNTs:

Multi-walled CNTs

OP:

Organophosphorus

OPH:

Organophosphorus hydrolase

PDMS:

Poly(dimethylsiloxane)

PNA:

Peptide nucleic acid

QCM:

Quartz crystal microbalance

SAM:

Self assembled monolayer

SEM:

Scanning electron microscopy

SNP:

Single-nucleotide polymorphism

SSB:

Single-stranded DNA binding protein

SWCNTs:

Single-walled CNTs

TNF-α:

Tumor necrosis factor-α gene

T-PSA:

Prostate-specific antigen

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Authors and Affiliations

  1. Department of Applied Physics, Graduate School of Engineering Osaka University, 2-1 Yamadaoka, Suita, Osaka, 565-0871, Japan

    Masato Saito, Ha Minh Hiep & Eiichi Tamiya

  2. Dpartment of Applied chemistry and Biotechnology, Okayama University of Science, 1-1 Ridai-cho, Kita-ku, Okayama, 700-0005, Japan

    Naoki Nagatani (Faculty of Engineering)

Authors
  1. Masato Saito
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  2. Ha Minh Hiep
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  3. Naoki Nagatani
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  4. Eiichi Tamiya
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Corresponding author

Correspondence to Eiichi Tamiya .

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Editors and Affiliations

  1. Saitama Industrial Technology Center, Kamiaoki 3-12-18, Kawaguchi-shi, Saitama, 333-0844, Japan

    Isao Endo

  2. School of Engineering, Dept. Bioengineering, University of Tokyo, Hongo 7-3-1, Tokyo, 113-8656, Japan

    Teruyuki Nagamune

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Saito, M., Hiep, H.M., Nagatani, N., Tamiya, E. (2009). Sensors. In: Endo, I., Nagamune, T. (eds) Nano/Micro Biotechnology. Advances in Biochemical Engineering / Biotechnology, vol 119. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2009_13

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