Abstract
We propose a dynamic scenario for the emergence and evolution of peptides on the primitive Earth, through a molecular engine (the primary pump), which works at ambient temperature and continuously generates, elongates and complexifies sequential peptides. This new scenario is based on a cyclic chemical reaction sequence that could have taken place on tidal beaches; it requires a buffered ocean, emerged land and a nitrosating atmosphere. We show that the primitive Earth during the Hadean may have satisfied all of these requirements. This scenario is not necessarily what actually happened, but it represents a global approach of peptide prebiotic synthesis, and most of its parts are accessible to experiment. As it develops, it may open up a gateway to the emergence of homochirality and the catalytic activities of peptides.
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References
Bartlett PD, Dittmer DC (1957). A kinetic study of the Leuchs anhydrides in aqueous solution. II. J. Am. Chem. Soc. 79: 2159–2161.
Bartlett PD, Jones RH (1957). A kinetic study of the Leuchs anhydrides in aqueous solution. I. J. Am. Chem. Soc. 79: 2153–2159.
Bengston M, Edstrom ED (1999). A new method for testing models of prebiotic peptide assembly. In: Advances in BioChirality, Pályi G, Zucchi C and Caglioti L (eds), Elsevier. pp 115–123.
Blair NE, Bonner WA (1980). Experiments on the amplification of optical activity. Origin of Life and Evolution of the Biosphere 10: 255–263.
Blair NE, Bonner WA (1981). A model for the enantiomeric enrichment of polypeptides on the primitive Earth. Origin of Life 11: 331–335.
Bohler C, Hill AR, Orgel LE (1996). Catalysis of the oligomerization of o-phospho-serine aspartic acid, or glutamic acid by cationic micelles. Origins of Life and Evolution of the Biosphere 26: 2–5.
Bowring SA, Williams IS (1999). Priscoan (7,00–4,03 Ga) orthogneisses from northwestern Canada. Contribution to Mineralogy and Petrology 134: 3–16.
Caldeira K, Kasting JF (1992). Susceptibility of the early Earth to irreversible glaciation caused by carbon dioxide clouds. Nature 359: 226–228.
Carbary JF, Morrison D, Romick GJ, Yee JH (2003). Leonid meteor spectrum from 110 to 860 nm. Icarus 161: 223–234.
Chyba CF (1990). Impact delivery and erosion of planetary oceans in the early inner solar system. Nature 343: 129–133.
Collet H, Boiteau L, Taillades J, Commeyras A (1999). Solid phase decarbamoylation of N-carbamoylpeptides and monoalkylureas using gaseous NOx: a new simple deprotection reaction with minimum waste. Tetrahedron Letters 40: 3355–3358.
Collet H, Bied C, Mion L, Taillades J, Commeyras A (1996). A new simple and quantitative synthesis of α-Aminoacid-N-Carboxyanhydrides. Tetrahedron Letters 37: 9043–9046.
Commeyras A, Collet H, Boiteau L, Taillades J, Vandenabeele-Trambouze O, Cottet H, Biron J-P, Plasson R, Mion L, Lagrille O, Martin H, Selsis F, Dobrijevic M (2002). Prebiotic Synthesis of Sequential Peptides on the Hadean Beach by a Molecular Engine Working with Nitrogen Oxides as Energy Sources. Polymer International 51: 661–665.
Commeyras A, Taillades J, Collet H, Mion L, Boiteau L, Trambouze-Vandenabeele O, Cottet H, Biron JP, Schué F, Giani O, Lagrille O, Plasson R, Vayaboury W, Martin H, Selsis F, Dobrijevic M, Geffard M (2001). La Terre, matrice de la Vie: émergence avant-gardiste des peptides sur les plages de l'Hadéen. In: L'environnement de la Terre Primitive, Gargaud M, Despois D, Parisot JP (eds.), Presses Universitaires de Bordeaux, pp 361–380.
Commeyras A, Taillades J, Collet H, Boiteau L, Pascal R, Vandenabeele-Trambouze O, Pascal R, Rousset A, Garrel L, Rossi JC, Cottet H, Biron JP, Lagrille O, Plasson R, Souaid E, Selsis F, Dobrijevic M (2003). Approche dynamique de la synthèse des peptides et de leurs précurseurs sur la Terre primitive. In: Les Traces du Vivant, Gargaud M, Despois D, Parisot JP (eds.). Presses Universitaires de Bordeaux, Bordeaux, France, pp 115–162.
De Duve C (1998). Clues from present-day biology: the thioester world. In: The Molecular Origin of Life, Brack A (ed.), Cambridge University Press. Cambridge, UK, pp 219–236.
Fox SW, Dose H (1977). Molecular Evolution, New York, Academic Press. New York, (USA).
Gesteland RF, Cech TR, Athins JF (1999). The RNA Word. 2nd edition, Cold Spring Harbor Laboratory Press. New York (USA).
Gilbert W (1986). The RNA World. Nature 319: 618.
Guinan E, Ribas I (2002). Our changing Sun: the role of solar nuclear evolution and magnetic activity on Earth's atmosphere and climate. ASP Conference Series, 269: 85–106.
Huber C, Wächtershäuser G (1998). Peptides by activation of amino acids with CO on (Ni,Fe)S surfaces: implications for the origin of life. Science 281: 670–672.
Idelson M, Blout ER (1958). Polypeptides. XVIII. A kinetic study of the polymerisation of amino acid N-carboxyanhydrides initiated by strong bases. J. Am. Chem. Soc. 79: 2387–2393.
Jenniskens P, Wilson MA, Packan D, Laux CO, Krüger CH, Boyd ID, Popova OP, Fonda M (2000). Meteors: A delivery mechanism of organic matter to the early Earth. Earth, Moon and Planets 82/83: 57–70.
Joyce GF, Orgel LE (1999). Prospects for understanding the origin of the RNA world. In: The RNA World. 2nd edn, Cold Spring Harbor Laboratory Press (New York), pp 49–77.
Kasting JF (1993). Earth's early atmosphere. Science 259: 920–926.
Kasting JK, Catling D (2003). Evolution of a habitable planet. Annual Review of Astronomy and Astrophysics 41: 429–463.
Kauffman SA (1993). The Origin of Order. Self-organisation and Selection in Evolution, 1st edn. Oxford University Press (see especially Chap. 7).
Lagrille O (2001). Nitrosation de N-Carbamoylaminoacides Solides par le mélange gazeux NO/O2. Synthèse de N-Carboxyanhydrides (Anhydrides de Leuchs). PhD thesis, Université de Montpellier 2 (France).
Lagrille O, Taillades J, Boiteau L, Commeyras A (2002). N-Carbamoyl Derivatives and their nitrosation by gazeous NOx –A new promissing tool in stepwise peptide synthesis. Eur. J. Org. Chem: 1026–1032.
Lahav N, Wite DH, Chang S (1978). Peptide formation in the prebiotic Era: thermal condensation of glycine in fluctuating clay environments. Science 201: 67–69.
Liu R, Orgel LE (1998). Polymerization of β-amino acids in aqueous solution. Orig. Life Evol. Biosphere 28: 47–60.
Luisi PL (2000). L'assemblage des macromolécules. La Recherche 336: 25–29.
Luisi PL, Walde P, Blocher M, Liu D (2000). Research on the origin of Life: membrane-assisted polycondensations of amino acids and peptides. Chimia 54: 52–53.
Lundberg RD, Doty P (1957). Polypeptides. XVII. A Study of the Kinetics of the Primary Amine-initiated Polymerisation of N-carboxy-anhydrides with special reference to configurational and stereochemical effects. J. Am. Chem. Soc. 78: 3961–3972.
Martin H (1986). Effect of steeper Archean geothermal gradient on geochemistry of subduction-zone magmas. Geology 14: 753–756.
Martin H (1987). Petrogenesis of Archaean trondhjemites, tonalites and granodiorites from eastern Finland: major and trace element geochemistry. Journal of Petrology 28: 921–953.
McCulloch MT, Bennet VC (1993). Evolution of the early Earth: constraints from 143Nd-142Nd isotopic systematics. Lithos 30: 237–255.
Mojzsis SJ, Krishnamurthy R, Arrhenius G (1999). Before RNA and after: Geophysical and geochemical constraints on molecular evolution. In: The RNA Word 2nd edn. Gesteland RF, Cech TR and Athins JF (eds.), Cold Spring Harbor Laboratory Press, pp 1–47.
Mojzsis SJ, Harrison MT, Pidgeon RT (2001). Oxygen-isotope evidence from ancient zircons for liquid water at the Earth's surface 4,300 Myr ago. Nature 409: 178–181.
Morrison D, Chapman CR, Slovic P (1994). The impact hazard. In: Hazards due to Comets and Asteroids, Gehrels T, Matthews MS and Schumann A (eds.). Univ. Arizona Press, Tucson, USA, pp 59–92.
Munoz Caro GM, Meierhenrich UJ, Schutte WA, Barbier B, Arcone Segovia A, Rosenbauer H, Thiemann WHP, Brack A, Greenberg GM (2002). Amino acids from ultraviolet irradiation of interstellar ice analogues. Nature 416: 403–406.
Navarro-Gonzalez R, Molina MJ, Molina LT (1998). Nitrogen fixation by volcanic lightning in the early Earth. Geophys. Res. Lett. 25: 3123–3126.
Navarro-Gonzalez R, McKay CP, Nna Mvondo D (2001). A possible nitrogen crisis for Archaean life due to reduced nitrogen fixation by lightning. Nature 412: 61–64.
Nicolis G, Prigogine I (1977). Self-organization in Nonequilibrium Systems. Wiley & Sons. New York (USA).
Orgel LE (1989). The origin of polynucleotide-directed protein synthesis. J. Mol. Evol. 29: 465–474.
Orgel LE (1998). Polymerization on the rocks: Theoretical introduction. Origins of Life and Evolution of the Biosphere 28: 227–237.
Paecht-Horowitz M, Eirich FR (1988). Origins of Life and Evolution of the Biosphere 18: 359.
Pascal R (2003). Catalysis by induced intramolecularity: what can be learned by mimicking enzymes with carbonyl compounds that covalently bind substrates? Eur. J. Org. Chem.: 1813–1824.
Pavlov AA, Kasting JF, Brown LL, Rages KA, Freedman R (2000). Greenhouse warming by CH4 in the atmosphere of early Earth. J. Geophys. Res. 105: 11981–11990.
Pizzarello S, Cronin JR (2000). Non-racemic amino acids in the Murray and Murchison meteorites. Géochimica Cosmochemica Acta 64: 329–338.
Plasson R, Biron JP, Cottet H, Commeyras A, Taillades J (2002). Kinetic study of α-aminoacids N-carboxyanhydrides polymérisation in aqueous solution using capillary electrophoresis. J. Chrom. A 952: 239–248.
Plasson R. (2003). Origine moléculaire de la vie: étude de la polymérisation de aminoacides N-carboxyanhydrides dans des conditions prébiotiques, par électrophorèse capillaire. PhD thesis, Université de Montpellier 2 (France).
Prinn RG, Fegley B (1987). Bolide impacts, acid rain, and biospheric traumas at the Cretaceous-Tertiary boundary. Earth and Planetary Science Letters 83: 1–4.
Rode BM, Eder AH, Yongyai Y (1997). Amino acid sequence preferences of the salt-induced peptide formation reaction in comparison to archaic cell protein composition. Inorganica Chemica Acta 254:309–314.
Rohlfing DL (1976). Thermal polyamino acids: synthesis at less than 100. Science 193: 68–69.
Rosenqvist J, Chassefière E (1995). Inorganic chemistry of O2 in a dense primitive atmosphere. Planet. Space Sci. 43: 3–10.
Selsis F (2000). Modèle d'évolution physico-chimique des atmosphères de planètes telluriques. Application à l'atmosphère primitive terrestre et aux planètes extrasolaires. PhD thesis, Université Bordeaux 1, France.
Selsis F, Despois D, Parisot J-P (2002). Signature of life on exoplanets: Can Darwin produce false positive detections? Astronomy and Astrophysics 388: 985–1003.
Shimoyama A, Ogasawara R (2002). Dipeptides and Diketopiperazines in the Yamato-791198 and Murchison Carbonaceous Chondrites. Orig. Life Evol. Biosphere 32: 165–179.
Sleep NH, Zahnle K (2001). Carbon dioxide cycling and implications for climate on ancient Earth. Journal of Geophysical Research 106: 1373–1399.
Taillades J, Collet H, Garrel L, Beuzelin I, Boiteau L, Choukroun H, Commeyras A (1999). N-Carbamoylaminoacid solid-gas nitrosation by NO/NOx : a new route to oligopeptides via α-aminoacid N-carboxyanhydride. Prebiotic implications. Journal of Molecular Evolution 48: 638–645.
Taillades J, Boiteau L, Beuzelin I, Lagrille O, Biron JP, Vayaboury W, Vandenabeele-Trambouze O, Giani O, Commeyras A (2001). A pH-dependent cyanate reactivity model: application to preparative N-carbamoylation of amino acids. Perkin Trans. 2: 1247–1253.
Tolstikhin IN, Marty B (1998). The evolution of terrestrial volatiles: a view from helium, neon, argon and nitrogen isotope modelling. Chem. Geol. 147: 27.
Toon OB, Zahnle K, Turco RP, Covey C (1994). Environmental perturbations caused by asteroid impacts, in Hazards due to comets and asteroids. Univ. Arizona Press, Tucson, USA, pp 791–826.
Turco RP, Toon OB, Park C, Whitten RC, Pollack JB, Noerdlinger P (1982). An analysis of the physical, chemical, optical, and historical consequence of the 1908 Tungunska meteor fall. Icarus 50: 1–52.
Wald G (1957). The origin of Optical Activity. Ann. NY Acad. Sci. 69: 352–368.
Weber AL (1998). Prebiotic aminoacid thioester synthesis: Thiol-dependent amino acid synthesis from formose substrate (formaldehyde and glycolaldehyde) and ammonia. Origins of Life and Evolution of the Biosphere 28: 259–270.
Wilde SA, Valley JW, Peck WH, Graham CM (2001). Evidence from detrital zircons for the existence of continental crust and oceans on the Earth 4.4 Ga ago. Nature 409: 175–178.
Zahnle K (1998). Origins of atmospheres. ASP Conf Series 148: Origins: 364.
Zahnle K, Kasting JF, Sleep N (1988). Impact production of NO and reduced species. In: LPI Contribution 673 (abstracts of the Topical conference on global catastrophes in Earth history: interdisciplinary conference on impacts, volcanism, and mass mortality, Snowbird, Utah, Oct. 20–23, 1988), Lunar & Planetary Institute, Houston, pp 223–224.
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Commeyras, A., Boiteau, L., Vandenabeele-Trambouze, O., Selsis, F. (2005). Peptide Emergence, Evolution and Selection on the Primitive Earth. In: Gargaud, M., Barbier, B., Martin, H., Reisse, J. (eds) Lectures in Astrobiology. Advances in Astrobiology and Biogeophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10913406_16
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