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Keywords

Septic Shock Disseminate Intravascular Coagulation Necrotizing Fasciitis Forensic Autopsy Central Pontine Myelinolysis 
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References

  1. 1.
    Tsokos M, Püschel K. Iatrogenic Staphylococcus aureus septicaemia following intravenous and intramuscular injections: clinical course and pathomorphological findings. Int J Legal Med 1999;112:303–308.PubMedGoogle Scholar
  2. 2.
    Heinemann A, Tsokos M, Püschel K. Medico-legal aspects of pressure sores. Leg Med 2003;5(suppl 1):S263–S266.Google Scholar
  3. 3.
    Tsokos M. Pathology of sepsis. Part I: forensic problems arising in the postmortem diagnosis of death due to sepsis. Jpn J Forens Pathol 2002;8:72–77.Google Scholar
  4. 4.
    Rutty GN, Busuttil A. Necrotizing fasciitis: reports of three fatal cases simulating and resulting from ssaults. Am J Forensic Med Pathol 2000;21:151–154.CrossRefPubMedGoogle Scholar
  5. 5.
    Caplan ES, Kluge RM. Gas gangrene: review of 34 cases. Arch Intern Med 1976;136:788–791.CrossRefPubMedGoogle Scholar
  6. 6.
    Siemann M, Koch-Dorfler M, Rabenhorst G. Clostridium difficile-associated diseases. The clinical courses of 18 fatal cases. Intensive Care Med 2000;26:416–421.CrossRefPubMedGoogle Scholar
  7. 7.
    Türk EE, Tsokos M, Delling G. Autopsy-based assessment of extent and type of osteomyelitis in advanced-grade sacral decubitus ulcers: a histopathologic study. Arch Pathol Lab Med 2003;127:1599–1602.PubMedGoogle Scholar
  8. 8.
    Tsokos M, Heinemann A, Püschel K. Pressure sores: epidemiology, medico-legal implications and forensic argumentation concerning causality. Int J Legal Med 2000;113:283–287.PubMedGoogle Scholar
  9. 9.
    Sperhake JP, Tsokos M. Pathological features of Waterhouse-Friderichsen syndrome in infancy and childhood. In: Tsokos M, editor. Forensic pathology reviews, vol. 1. Totowa, NJ: Humana Press, 2004: 219–231.Google Scholar
  10. 10.
    Anders S, Koops E, Tsokos M, Mack D. Letale “nicht-tropische” Pyomyositis-Falldarstellungen und Literaturübersicht. Rechtsmedizin 2000;10:159–165.Google Scholar
  11. 11.
    Türk EE, Sperhake JP, Tsokos M. Pseudomembranous colitis with fatal outcome in a 43-year-old man. Leg Med 2002;4:246–250.CrossRefGoogle Scholar
  12. 12.
    Tsokos M. Fatal Waterhouse-Friderichsen syndrome due to Ewingella americana infection. Am J Forensic Med Pathol 2003;24:41–44.PubMedGoogle Scholar
  13. 13.
    Matschke J, Tsokos M. Post-traumatic meningitis: histomorphological findings, postmortem microbiology and forensic implications. Forensic Sci Int 2001;115:199–205.CrossRefPubMedGoogle Scholar
  14. 14.
    Bonds LA, Gaido L, Woods JE, Cohn DL, Wilson ML. Infectious diseases detected at autopsy at an urban public hospital, 1996–2001. Am J Clin Pathol 2003;119:866–872.PubMedGoogle Scholar
  15. 15.
    Roosen J, Frans E, Wilmer A, Knockaert DC, Bobbaers H. Comparison of premortem clinical diagnoses in critically ill patients and subsequent autopsy findings. Mayo Clin Proc 2000;75:562–567.PubMedGoogle Scholar
  16. 16.
    Nseir S, Marquette CH. Diagnosis of hospital-acquired pneumonia: postmortem studies. Infect Dis Clin North Am 2003;17:707–716.CrossRefPubMedGoogle Scholar
  17. 17.
    Koch S, Hohne FM, Tietz HJ. Incidence of systemic mycoses in autopsy material. Mycoses 2004; 47:40–46.PubMedGoogle Scholar
  18. 18.
    Tsokos M, Pufe T, Paulsen F, Anders S, Mentlein R. Pulmonary expression of vascular endothelial growth factor in sepsis. Arch Pathol Lab Med 2003;127:331–335.PubMedGoogle Scholar
  19. 19.
    Madden JF, Burchette JL Jr, Hale LP. Pathology of parainfluenza virus infection in patients with congenital immunodeficiency syndromes. Hum Pathol 2004;35:594–603.CrossRefPubMedGoogle Scholar
  20. 20.
    Kutta H, Steven P, Tillmann BN, Tsokos M, Paulsen FP. Region-specific immunological response of the different laryngeal compartments: significance of larynx-associated lymphoid tissue. Cell Tissue Res 2003;311:365–371.PubMedGoogle Scholar
  21. 21.
    Tsokos M, Anders S, Paulsen F. Lectin binding patterns of alveolar epithelium and subepithelial seromucous glands of the bronchi in sepsis and controls: an approach to characterize the nonspecific immunological response of the human lung to sepsis. Virchows Arch 2002;440:181–186.PubMedGoogle Scholar
  22. 22.
    Paulsen F, Pufe T, Conradi L, Varoga D, Tsokos M, Papendieck J, Petersen W. Antimicrobial peptides are expressed and produced in healthy and inflamed human synovial membranes. J Pathol 2002; 198:369–377.CrossRefPubMedGoogle Scholar
  23. 23.
    Pufe T, Paulsen F, Petersen W, Mentlein R, Tsokos M. The angiogenic peptide vascular endothelial growth factor (VEGF) is expressed in chronic sacral pressure ulcers. J Pathol 2003;200:130–136.CrossRefPubMedGoogle Scholar
  24. 24.
    Tsokos M, Paulsen F. Expression of pulmonary lactoferrin in sudden-onset and slow-onset asthma with fatal outcome. Virchows Arch 2002;441:494–499.CrossRefPubMedGoogle Scholar
  25. 25.
    Tsokos M, Fehlauer F, Püschel K. Immunohistochemical expression of E-selectin in sepsis-induced lung injury. Int J Legal Med 2000;113:338–342.PubMedGoogle Scholar
  26. 26.
    Tsokos M, Püschel K. Postmortem bacteriology in forensic pathology: diagnostic value and interpretation. Leg Med 2001;3:15–22.CrossRefGoogle Scholar
  27. 27.
    Thomsen JL, Søgaard P. Bacteria in lung tissue from an autopsy population of alcoholics. Forensic Sci Int 1999;99:53–59.CrossRefPubMedGoogle Scholar
  28. 28.
    Pääkkö P, Säkioja T, Hirvonen J, Nurmi T, Lahti R, Sutinen S. Postmortem radiographic, histological and bacteriological studies of terminal respiratory infections and other pulmonary lesions in hospital and non-hospital necropsies. J Clin Pathol 1984;37:1282–1288.PubMedGoogle Scholar
  29. 29.
    Lockemann U, Püschel K. HIV-1 prevalence among drug deaths: a multicenter study. Forensic Sci Int 1993;62:89–93.CrossRefPubMedGoogle Scholar
  30. 30.
    Finn SP, Leen E, English L, O’Briain DS. Autopsy findings in an outbreak of severe systemic illness in heroin users following injection site inflammation: an effect of Clostridium novyi exotoxin? Arch Pathol Lab Med 2003;127:1465–1470.PubMedGoogle Scholar
  31. 31.
    Dirnhofer R, Sonnabend O, Sonnabend W. Eine tödlich verlaufende Lebensmittelvergiftung durch Bacillus cereus. Z Rechtsmed 1977;80:139–145.PubMedGoogle Scholar
  32. 32.
    Fieguth A, Kleemann WJ, Bautsch W, Tröger HD. Neun Todesfälle nach Salmonellenepidemie in einem hannoverschen Altenheim. Rechtsmedizin 1995;5:50–52.Google Scholar
  33. 33.
    Kortelainen ML, Särkioja T. Fatal complications of intramuscular and intra-articular injections. Z Rechtsmed 1990;103:547–554.PubMedGoogle Scholar
  34. 34.
    Nields H, Kessler SC, Boisot S, Evans R. Streptococcal toxic shock syndrome presenting as suspected child abuse. Am J Forensic Med Pathol 1998;19:93–97.CrossRefPubMedGoogle Scholar
  35. 35.
    Bajanowski T, Rolf B, Jorch G, Brinkmann B. Detection of RNA viruses in sudden infant death (SID). Int J Legal Med 2003;117:237–240.PubMedGoogle Scholar
  36. 36.
    Dettmeyer R, Madea B. Unexpected death related to viral myocarditis. A survey of histological, immunohistochemical, and molecular pathological methods for the postmortem diagnosis. In: Tsokos M, editor. Forensic pathology reviews, vol. 2. Totowa, NJ: Humana Press, 2005:165–189.Google Scholar
  37. 37.
    Cubie HA, Duncan LA, Marshall LA, Smith NM. Detection of respiratory syncytial virus nucleic acid in archival postmortem tissue from infants. Pediatr Pathol Lab Med 1997;17:927–938.CrossRefPubMedGoogle Scholar
  38. 38.
    Tsokos M, Zöllner B, Feucht HH. Fatal influenza A infection with Staphylococcus aureus superinfection in a 49-year-old woman presenting as sudden death. Int J Legal Med 2005;119:40–43.PubMedGoogle Scholar
  39. 39.
    De Jongh DS, Loftis JW, Green GS, Shively JA, Minckler TM. Postmortem bacteriology: a practical method for routine use. Am J Clin Pathol 1968;49:424–428.PubMedGoogle Scholar
  40. 40.
    Koneman EW, Minckler TM, Shires DB, De Jongh DS. Postmortem bacteriology: II. Selection of cases for culture. Am J Clin Pathol 1971;55:17–23.PubMedGoogle Scholar
  41. 41.
    Klastersky J, Daneau D, Verhest A. Significance of routine post-mortem bacteriological cultures. Pathol Biol 1972;20:843–847.PubMedGoogle Scholar
  42. 42.
    Wilson WR, Dolan CT, Washington JA, Brown AL, Ritts RE. Clinical significance of postmortem cultures. Arch Pathol 1972;94:244–249.PubMedGoogle Scholar
  43. 43.
    O’Toole WF, Saxena HMK, Golden A, Ritts RE. Studies of postmortem microbiology using sterile autopsy technique. Arch Pathol 1965;80:540–547.PubMedGoogle Scholar
  44. 44.
    Silver H, Sonnenwirth AC. A practical and efficacious method for obtaining significant postmortem blood cultures. Am J Clin Pathol 1969;52:433–437.PubMedGoogle Scholar
  45. 45.
    Tsokos M, Matschke J, Cordes O, Heinemann A, et al. Bakterielle Meningitis als Ursache des plötzlichen Todes-Phänomenologie, Histomorphologie und Erregerspektrum. Rechtsmedizin 2000; 10:128–134.Google Scholar
  46. 46.
    Roberts FJ. Procurement, interpretation, and value of postmortem cultures. Eur J Clin Microbiol Infect Dis 1998;17:821–827.CrossRefPubMedGoogle Scholar
  47. 47.
    Norris C, Pappenheimer AM. A study of pneumococci and allied organisms in human mouths and lungs after death. J Exp Med 1905;7:450–472.CrossRefGoogle Scholar
  48. 48.
    Torres A, Fabregas N, Ewig S, de la Bellacasa JP, Bauer TT, Ramirez J. Sampling methods for ventilator-associated pneumonia: validation using different histologic and microbiological references. Crit Care Med 2000;28:2799–2804.PubMedGoogle Scholar
  49. 49.
    Leal-Noval SR, Marquez-Vacaro JA, Garcia-Curiel A, et al. Nosocomial pneumonia in patients undergoing heart surgery. Crit Care Med 2000;28:935–940.PubMedGoogle Scholar
  50. 50.
    Thomas S, Raman R, Idikula J, Brahmadathan N. Alterations in oropharyngeal flora in patients with a nasogastric tube: a cohort study. Crit Care Med 1992;20:1677–1680.PubMedGoogle Scholar
  51. 51.
    Roberts FJ. The association of antimicrobial therapy with postmortem spleen culture in bacteremic patients. Am J Clin Pathol 1987;87:770–772.PubMedGoogle Scholar
  52. 52.
    Roberts FJ. A review of postmortem bacteriological cultures. Can Med Assoc J 1969;100:70–74.PubMedGoogle Scholar
  53. 53.
    Wood WH, Oldstone M, Schultz RB. A re-evaluation of blood culture as an autopsy procedure. Am J Clin Pathol 1965;43:241–247.PubMedGoogle Scholar
  54. 54.
    Carpenter HM, Wilkins R. Autopsy bacteriology: review of 2033 cases. Arch Pathol 1964;79:73–81.Google Scholar
  55. 55.
    Mort TC, Yeston NS. The relationship of pre mortem diagnoses and post mortem findings in a surgical intensive care unit. Crit Care Med 1999;27:299–303.PubMedGoogle Scholar
  56. 56.
    Saito A, Hara K, Yamaguchi K, Usui T. Pulmonary infection due to anaerobes in a hospital autopsy survey. Rev Infect Dis 1984;6(suppl 1):S128–S131.PubMedGoogle Scholar
  57. 57.
    Adrie C, Pinsky MR. The inflammatory balance in human sepsis. Intensive Care Med 2000;26: 364–375.CrossRefPubMedGoogle Scholar
  58. 58.
    Sommers MS. The cellular basis of septic shock. Crit Care Nurs Clin North Am 2003;15:13–25.PubMedGoogle Scholar
  59. 59.
    le Roux P. An update on the pathophysiology of sepsis. SADJ 2004;59:163,165.PubMedGoogle Scholar
  60. 60.
    Thijs LG, Hack CE. Time course of cytokine levels in sepsis. Intensive Care Med 1995;21:258–263.CrossRefGoogle Scholar
  61. 61.
    Tracey KJ, Lowry SF. The role of cytokine mediators in septic shock. Adv Surg 1990;23:21–56.PubMedGoogle Scholar
  62. 62.
    Weigand MA, Horner C, Bardenheuer HJ, Bouchon A. The systemic inflammatory response syndrome. Best Pract Res Clin Anaesthesiol 2004;18:455–475.CrossRefPubMedGoogle Scholar
  63. 63.
    Takala A, Nupponen I, Kylanpaa-Back ML, Repo H. Markers of inflammation in sepsis. Ann Med 2002;34:614–623.PubMedGoogle Scholar
  64. 64.
    Bone RC. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation. Crit Care Med 1996;24:163–172.PubMedGoogle Scholar
  65. 65.
    Bone RC. Immunologic dissonance: a continuing evolution in our understanding of the systemic inflammatory response syndrome (SIRS) and the multiple organ dysfunction syndrome (MODS). Ann Intern Med 1996;125:680–687.PubMedGoogle Scholar
  66. 66.
    Goris RJ. Shock, sepsis and multiple organ failure: the result of the whole body inflammation. In: Schlag G, Redl H, editors. Pathophysiology of shock, sepsis, and organ failure. Berlin: Springer, 1993:7–24.Google Scholar
  67. 67.
    Raraty MG, Connor S, Criddle DN, Sutton R, Neoptolemos JP. Acute pancreatitis and organ failure: pathophysiology, natural history, and management strategies. Curr Gastroenterol Rep 2004; 6:99–103.PubMedGoogle Scholar
  68. 68.
    Larmann J, Theilmeier G. Inflammatory response to cardiac surgery: cardiopulmonary bypass versus non-cardiopulmonary bypass surgery. Best Pract Res Clin Anaesthesiol 2004;18:425–438.CrossRefPubMedGoogle Scholar
  69. 69.
    American College of Chest Physicians/ Society of Critical Care Medicine Consensus Conference. Definition for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Crit Care Med 1992;20:864–874.Google Scholar
  70. 70.
    Singer M, De Santis V, Vitale D, Jeffcoate W. Multiorgan failure is an adaptive, endocrine-mediated, metabolic response to overwhelming systemic inflammation. Lancet 2004;364:545–548.CrossRefPubMedGoogle Scholar
  71. 71.
    Bone RC. The sepsis syndrome: definition and general approach to management. Clin Chest Med 1996;17:175–181.CrossRefPubMedGoogle Scholar
  72. 72.
    Bone RC. Sepsis and SIRS. Nephrol Dial Transplant 1994;9(suppl 4):99–103.PubMedGoogle Scholar
  73. 73.
    Bone RC. Sepsis and its complications: the clinical problem. Crit Care Med 1994;22:8–11.Google Scholar
  74. 74.
    Karzai W, Reinhart K. Sepsis: definitions and diagnosis. Int J Clin Pract Suppl 1998;95:44–48.PubMedGoogle Scholar
  75. 75.
    Ellrodt AG. Sepsis and septic shock. Emerg Med Clin North Am 1986;4:809–840.PubMedGoogle Scholar
  76. 76.
    Tsokos M, Mack D, Püschel K Postmortale bakteriologische Diagnostik. Entnahmetechnik, Untersuchungsmaterial, limitierende Faktoren, diagnostische Wertigkeit und Interpretation. Rechtsmedizin 2002;12:59–64.CrossRefGoogle Scholar
  77. 77.
    O’Boyle CJ, MacFie J, Mitchell CJ, Johnstone D, Sagar PM, Sedman PC. Microbiology of bacterial translocation in humans. Gut 1998;42:29–35.PubMedGoogle Scholar
  78. 78.
    Woodcock NP, Robertson J, Morgan DR, Gregg KL, Mitchell CJ, MacFie J. Bacterial translocation and immunohistochemical measurement of gut immune function. Clin Pathol 2001;54:619–623.Google Scholar
  79. 79.
    Lasch HG, Heene DL, Huth K, Sandritter W. Pathophysiology, clinical manifestations and therapy of consumption-coagulopathy (“Verbrauchskoagulopathie:) Am J Cardiol 1967;20:381–391.CrossRefPubMedGoogle Scholar
  80. 80.
    Lindner J, Schütte B. Infektion und Blutgerinnung aus pathologisch-anatomischer Sicht. In: Marx R, Thies HA, editors. Infektion, blutgerinnung und hämostase. Stuttgart: Schattauer, 1977:9–43.Google Scholar
  81. 81.
    Müller-Berghaus G. Sepsis und Blutgerinnung. Behring Inst Mitt 1986;79:131–141.PubMedGoogle Scholar
  82. 82.
    Svanbom M. A prospective study on septicemia. II. Clinical manifestations and complications, results of antimicrobial treatment and report of a follow-up study. Scand J Infect Dis 1980; 12:189–206.PubMedGoogle Scholar
  83. 83.
    Remmele W, Harms D. Zur pathologischen Anatomie des Kreislaufschocks beim Menschen. I. Mikrothrombose der peripheren Blutgefäße. Klin Wochenschr 1968;46:352–357.PubMedGoogle Scholar
  84. 84.
    Hamilton PJ, Stalker AL, Douglas AS. Disseminated intravascular coagulation. A review. J Clin Pathol 1978,31:609–619.PubMedGoogle Scholar
  85. 85.
    Evans TJ, Krausz T. Pathogenesis and pathology of shock. In: Anthony PP, MacSween RNM, editors. Recent advances in histopathology. Edinburgh: Churchill Livingstone, 1994:21–47.Google Scholar
  86. 86.
    Remmele W, Goebel U. Zur pathologischen Anatomie des Kreislaufschocks beim Menschen. IV. Pathomorphologie der Schocklunge. Klin Wochenschr 1973;51:25–36.PubMedGoogle Scholar
  87. 87.
    Martin AM, Soloway HB, Simmons RL. Pathologic anatomy of the lungs following shock and trauma. J Trauma 1968;8:687–698.PubMedGoogle Scholar
  88. 88.
    Schlag G, Redl H, Öhlinger W, Davies J. Morphological changes in adult respiratory distress syndrome: experimental and clinical data. In: Schlag G, Redl H, editors. Pathophysiology of shock, sepsis, and organ failure. Berlin: Springer, 1993:702–711.Google Scholar
  89. 89.
    Müller-Höcker J, Haerty W. Pathomorphological aspects of the heart in septic patients. In: Schlag G, Redl H, editors. Pathophysiology of shock, sepsis, and organ failure. Berlin: Springer, 1993:853–858.Google Scholar
  90. 90.
    Fernandes Junior CJ, Iervolino M, Neves RA, Sampaio EL, Knobel E. Interstitial myocarditis in sepsis. Am J Cardiol 1994;74:958.PubMedGoogle Scholar
  91. 91.
    Müller KM. Pathologisch-anatomische Organbefunde bei Sepsis. In: Lawin P, Peter K, Hartenauer U, editors. Infektion-Sepsis-Peritonitis. Schriftenreihe Intensivmedizin, Notfallmedizin, Anästhesiologie, vol. 37. Stuttgart,: Georg Thieme, 1982:27–46.Google Scholar
  92. 92.
    Dinges HP, Schlag G, Redl H. Morphology of the liver in shock. In: Schlag G, Redl H, editors. Pathophysiology of shock, sepsis, and organ failure. Berlin: Springer, 1993:257–264.Google Scholar
  93. 93.
    Gregory SH, Wing EJ. Neutrophil-Kupffer-cell interaction: a critical component of host defenses to systemic bacterial infections. J Leukoc Biol 2002;72:239–248.PubMedGoogle Scholar
  94. 94.
    Gregory SH, Sagnimeni AJ, Wing EJ. Bacteria in the bloodstream are trapped in the liver and killed by immigrating neutrophils. J Immunol 1996;157:2514–2520.PubMedGoogle Scholar
  95. 95.
    Caruana JA Jr, Montes M, Camara DS, Ummer A, Potmesil SH, Gage AA. Functional and histopathologic changes in the liver during sepsis. Surg Gynecol Obstet 1982;154:653–656.PubMedGoogle Scholar
  96. 96.
    Remmele W, Loeper H. Zur pathologischen Anatomie des Kreislaufschocks beim Menschen. IV. Pathomorphologie der Schockleber. Klin Wochenschr 1973;51:10–24.PubMedGoogle Scholar
  97. 97.
    Feig JA, Cina SJ. Evaluation of characteristics associated with acute splenitis (septic spleen) as markers of systemic infection. Arch Pathol Lab Med 2001;125:888–891.PubMedGoogle Scholar
  98. 98.
    Ruchti C. Pathomorphologische Befunde nach Intensivtherapie. Schweiz Med Wochenschr 1986; 116:694–698.PubMedGoogle Scholar
  99. 99.
    Rutty GN. The pathology of shock versus post-mortem change. In: Rutty GN, editor. Essentials of autopsy practice. London: Springer, 2004:93–127.Google Scholar
  100. 100.
    Sprung CL, Peduzzi PN, Shatney CH, et al. Impact of encephalopathy on mortality in the sepsis syndrome. The Veterans Administration Systemic Sepsis Cooperative Study Group. Crit Care Med 1990;18:801–816.PubMedGoogle Scholar
  101. 101.
    Eidelman LA, Putterman D, Putterman C, Sprung CL. The spectrum of septic encephalopathy. Definitions, etiologies, and mortalities. JAMA 1996;275:470–473.CrossRefPubMedGoogle Scholar
  102. 102.
    Jackson AC, Gilbert JJ, Young GB, Bolton CF. The encephalopathy of sepsis. Can J Neurol Sci 1985;12:303–307.PubMedGoogle Scholar
  103. 103.
    Skullerud K, Andersen SN, Lundevall J. Cerebral lesions and causes of death in male alcoholics. A forensic autopsy study. Int J Legal Med 1991;104:209–213.CrossRefPubMedGoogle Scholar
  104. 104.
    Graham DI, Behan PO, More IA. Brain damage complicating septic shock: acute haemorrhagic leucoencephalitis as a complication of the generalised Shwartzman reaction. J Neurol Neurosurg Psychiatry 1979;42:19–28.PubMedGoogle Scholar
  105. 105.
    Pendlebury WW, Perl DP, Munoz DG. Multiple microabscesses in the central nervous system: a clinicopathologic study. J Neuropathol Exp Neurol 1989;48:290–300.PubMedGoogle Scholar
  106. 106.
    Sharshar T, Annane D, de la Grandmaison GL, Brouland JP, Hopkinson NS, Francoise G. The neuropathology of septic shock. Brain Pathol 2004;14:21–33.PubMedGoogle Scholar
  107. 107.
    Schlag G, Redl H, Davies J, van Vuuren CJJ, Smuts P. Live Escherichia coli sepsis models in baboons. In: Schlag G, Redl H, editors. Pathophysiology of shock, sepsis, and organ failure. Berlin: Springer, 1993:1078–1107.Google Scholar
  108. 108.
    McGovern VJ. Shock revisited. Pathol Annu 1984;19:15–36.PubMedGoogle Scholar
  109. 109.
    Smith MI, Vickers AB. Natural history of treated and untreated patients with septicaemia. Lancet 1960;1:1318–1322.PubMedGoogle Scholar
  110. 110.
    Stevens DL, Bryant AE. The role of clostridial toxins in the pathogenesis of gas gangrene. Clin Infect Dis 2002;35(suppl 1):S93–S100.PubMedGoogle Scholar
  111. 111.
    Ansaloni L, Acaye GL. Absence of neutropenia in African patients with AIDS and associated pyomyositis. East Afr Med J 1994;71:736–738.PubMedGoogle Scholar
  112. 112.
    Biviji AA, Paiement GD, Steinbach LS. Musculoskeletal manifestation of human immunodeficiency virus infection. J Am Acad Orthop Surg 2002;10:312–320.PubMedGoogle Scholar
  113. 113.
    Türk EE, Tsokos M. Iliopsoas muscle bleeding as a complication of septic disseminated intravascular coagulation. Virchows Arch 2003;443:106–107.CrossRefPubMedGoogle Scholar
  114. 114.
    Türk EE. Iliopsoas muscle hemorrhage presenting at autopsy. In: Tsokos M, editor. Forensic pathology reviews, vol. 1. Totowa, NJ: Humana Press, 2004:341–353.Google Scholar
  115. 115.
    Czermak BJ, Breckwoldt M, Ravage ZB, et al. Mechanisms of enhanced lung injury during sepsis. Am J Pathol 1999;154:1057–1065.PubMedGoogle Scholar
  116. 116.
    Kaplan RL, Sahn SA, Petty TL. Incidence and outcome of respiratory distress syndrome in gramnegative sepsis. Arch Intern Med 1979;139:867–869.PubMedGoogle Scholar
  117. 117.
    Weiland JE, Davis WB, Holter JF, Mohammed JR, Dorinsky PM, Gadek JE. Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. Am Rev Respir Dis 1986;133:218–225.PubMedGoogle Scholar
  118. 118.
    Ertel W, Morrison MH, Wang P, Zheng F, Ayala A, Chaudry ICH. The complex patterns of cytokines in sepsis. Ann Surg 1991;214:141–148.PubMedGoogle Scholar
  119. 119.
    Thijs LG, Hack CE. Time course of cytokine levels in sepsis. Intensive Care Med 1995;21:258–263.CrossRefGoogle Scholar
  120. 120.
    Tracey KJ, Lowry SF. The role of cytokine mediators in septic shock. Adv Surg 1990;23:21–56.PubMedGoogle Scholar
  121. 121.
    Strieter RM, Kunkel SL. Acute lung injury: the role of cytokines in the elicitation of neutrophils. J Invest Med 1994;42:640–651.Google Scholar
  122. 122.
    Carlos TM, Harlan JM. Leukocyte-endothelial adhesion molecules. Blood 1994;84:2068–2101.PubMedGoogle Scholar
  123. 123.
    Osborn L. Leukocyte adhesion to endothelium in inflammation. Cell 1990;62:3–6.CrossRefPubMedGoogle Scholar
  124. 124.
    Lukacs NW, Ward PA. Inflammatory mediators, cytokines, and adhesion molecules in pulmonary inflammation and injury. Adv Immunol 1996;62:257–304.PubMedGoogle Scholar
  125. 125.
    Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1990;76:301–314.Google Scholar
  126. 126.
    Ebnet K, Vestweber D. Molecular mechanisms that control leukocyte extravasation: the selectins and the chemokines. Histochem Cell Biol 1999;112:1–23.CrossRefPubMedGoogle Scholar
  127. 127.
    Lasky LA. Lectin cell adhesion molecules (LEC-CAMs): a new family of cell adhesion proteins involved with inflammation. J Cell Biochem 1991;45:139–146.CrossRefPubMedGoogle Scholar
  128. 128.
    Lasky LA. Selectins: interpreters of cell-specific carbohydrate information during inflammation. Science 1992;258:964–968.PubMedGoogle Scholar
  129. 129.
    Ley K, Allietta M, Bullard DC, Morgan S. Importance of E-selectin for firm leukocyte adhesion in vivo. Circ Res 1998;83:287–294.PubMedGoogle Scholar
  130. 130.
    Butcher EC. Leukocyte-endothelial cell recognition: three (ore more) steps to specificity and diversity. Cell 1991;67:1033–1036.CrossRefPubMedGoogle Scholar
  131. 131.
    Schultz MJ, Rijneveld AW, van Deventer SJH, van der Poll T. Cytokines and host defense in pneumonia. Intensivmed 1999;36:270–275.CrossRefGoogle Scholar
  132. 132.
    Dobrina A, Menegazzi R, Carlos TM, et al. Mechanisms of eosinophil adherence to cultured vascular endothelial cells. Eosinophils bind to the cytokine-induced ligand vascular cell adhesion molecule-1 via the very late activation antigen-4 integrin receptor. J Clin Invest 1991;88:20–26.PubMedGoogle Scholar
  133. 133.
    Meerschaert J, Furie MB. The adhesion molecules used by monocytes for migration across endothelium include CD11a/CD18, CD11b/CD18, and VLA-4 on monocytes and ICAM-1, VCAM-1, and other ligands on endothelium. J Immunol 1995;154:4099–4112.PubMedGoogle Scholar
  134. 134.
    Kassner PD, Teixidó J, Chan BM, Parker CM, Hemler ME. Analyses of VLA-4 structure and function. Adv Exp Med Biol 1992;323:163–170.PubMedGoogle Scholar
  135. 135.
    Li XC, Miyasaka M, Issekutz TB. Blood monocyte migration to acute lung inflammation involves both CD11/CD18 and very late activation antigen-4 dependent and independent pathways. J Immunol 1998;161:6258–6264.PubMedGoogle Scholar
  136. 136.
    Tsokos M, Fehlauer F. Postmortem markers of sepsis: a quantitative immunohistochemical study using VLA-4 (CD49d/CD29) and ICAM-1 (CD54) for the detection of sepsis-induced lung injury. Int J Legal Med 2001;114:291–294.PubMedGoogle Scholar
  137. 137.
    Drake TA, Cheng J, Chang A, Taylor FB. Expression of tissue factor, thrombomodulin, and E-selectin in baboons with lethal Escherichia coli sepsis. Am J Pathol 1993;142:1458–1470.PubMedGoogle Scholar
  138. 138.
    Redl H, Dinges HP, Buurman WA, et al. Expression of endothelial leukocyte adhesion molecule-1 in septic but not traumatic/hypovolemic shock in the baboon. Am J Pathol 1991;139:461–466.PubMedGoogle Scholar
  139. 139.
    Müller AM, Cronen C, Müller KM, Kirkpatrick CJ. Heterogeneous expression of cell adhesion molecules by endothelial cells in ARDS. J Pathol 2002;198:270–275.CrossRefPubMedGoogle Scholar
  140. 140.
    Tsokos M. Immunohistochemical detection of sepsis-induced lung injury in human autopsy material. Leg Med 2003;5:73–86.CrossRefGoogle Scholar
  141. 141.
    Tsokos M, Anders S, Paulsen F, Fehlauer F, Püschel K. Comparative evaluation of pulmonary lactoferrin and lysozyme immunoreactivity for the postmortem diagnosis of death due to sepsis. Virchows Arch 2001;438:376–381.CrossRefPubMedGoogle Scholar
  142. 142.
    Dashefsky B, Teele DW, Klein JO. Unsuspected meningococcemia. J Pediatr 1983;102:69–72.PubMedGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2006

Authors and Affiliations

  • Michael Tsokos
    • 1
  1. 1.Institute of Legal Medicine, Department of Forensic PathologyUniversity of HamburgHamburgGermany

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