Skip to main content

Physics and Instrumentation in PET

  • Chapter
Positron Emission Tomography

Concluding Remarks

PET detectors and instrumentation have developed into sophisticated clinical tools, but further scope exists to develop higher-sensitivity, higher-resolution devices. There are now a number of scintillator crystals employed in commercial scanners, each with their own unique characteristics, including price. The range of scintillators may expand even further, especially if time-of-flight machines are developed. Light-collection technology may move away from photomultiplier tubes to solid-state devices (photodiodes) which will improve coupling and increase the bandwidth for data collection and processing by reducing the multiplexing of the signals.

Scanner design will continue to evolve and provide challenges in terms of photon detection, discrimination, and performance. Developments in basic physics will underpin many of these enhancements.

Chapter reproduced from Valk PE, Bailey DL, Townsend DW, Maisey MN. Positron Emission Tomography: Basic Science and Clinical Practice. Springer-Verlag London Ltd 2003, 41–67.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 219.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 379.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. Klein O, Nishina Y. Uber die streuung von strahlung durch frei elektronen nach der neuen relativistischen quantendynamik von Dirac. Z Physik 1928;52:853–868.

    Article  Google Scholar 

  2. Hubbell JH. Review of photon interaction cross section data in the medical and biological context. Phys Med Biol 1999;44(1):R1–22.

    Article  PubMed  CAS  Google Scholar 

  3. Hubbell JH. Photon cross sections, attenuation coefficients, and energy absorption coefficients from 10 keV to 100 GeV: National Bureau of Standards, US Dept of Commerce; 1969.

    Google Scholar 

  4. ICRU. Tissue substitutes in radiation dosimetry and measurement. Bethesda, MD, USA: International Commission on Radiation Units and Measurements; 1989. Report No. 44.

    Google Scholar 

  5. Townsend DW, Frey P, Jeavons A, Reich G, Tochon-Danguy HJ, Donath A, et al. High-density avalanche chamber (HIDAC) positron camera. J Nucl Med 1987;28:1554–62.

    PubMed  CAS  Google Scholar 

  6. Jeavons AP, Chandler RA, Dettmar CAR. A 3D HIDAC-PET camera with sub-millimetre resolution for imaging small animals. IEEE Trans Nucl Sci 1999;NS-46:468–73.

    Article  Google Scholar 

  7. Knoll GF. Radiation detection and measurement. 2nd ed. New York: John Wiley and Sons; 1988.

    Google Scholar 

  8. Karp JS, Muehllehner G, Geagan MJ, Freifelder R. Whole-body PET scanner using curve-plate NaI(Tl) detectors. J Nucl Med 1998;39:50P(abstract).

    Google Scholar 

  9. Melcher CL, Schweitzer JS. Cerium-doped lutetium oxyorthorthsilicate: a fast, efficient new scintillator. IEEE Trans Nucl Sci 1992;39(4):502–5.

    Article  CAS  Google Scholar 

  10. Lecomte R, Cadorette J, Richard P et al. Design and engineering aspects of a high-resolution positron tomograph for small-animal imaging. IEEE Trans Nucl Sci 1996;NS-41(4):1446–52.

    Google Scholar 

  11. Ziegler SI, Pichler BJ, Boening G, Rafecas M, Pimpl W, Lorenz E, et al. A prototype high-resolution animal positron tomograph with avalanche photodiode arrays and LSO crystals. Eur J Nucl Med 2001;28:136–43.

    Article  PubMed  CAS  Google Scholar 

  12. Cherry SR, Shao Y, Silverman RW, Chatziioannou A, Meadors K, Siegel S, et al. MicroPET: A high-resolution PET scanner for Imaging small animals. IEEE Trans Nucl Sci 1997;44:1161–6.

    Article  CAS  Google Scholar 

  13. Casey ME, Nutt R. A multicrystal, two-dimensional BGO detector system for positron emission tomography. IEEE Trans Nucl Sci 1986;NS-33(1):460–3.

    Article  CAS  Google Scholar 

  14. Wong W, Uribe J, Hicks K, Hu G. An analog decoding BGO block detector using circular photomultipliers. IEEE Trans Nucl Sci 1995;NS-42:1095–101.

    Article  Google Scholar 

  15. Adam LE, Zaers H, Ostertag H, Trojan H, Bellemann ME, Brix G. Performance evaluation of the whole-body PET scanner ECAT EXACT HR+ following the IEC standard. IEEE Trans Nucl Sci 1997;NS-44:1172–9.

    Article  Google Scholar 

  16. Carrier C, Martel C, Schmitt C, Lecomte R. Design of a high-resolution positron emission tomograph using solid scintillation detectors. IEEE Trans Nucl Sci 1988;NS-35(1):685–90.

    Article  Google Scholar 

  17. Huber JS, Moses WW, Derenzo SE, Ho MH, Andreaco MS, Paulus MJ, et al. Characterization of a 64-channel PET detector using photodiodes for crystal identification. IEEE Trans Nucl Sci 1997;NS-44:1197–201.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2005 Springer-Verlag London Limited

About this chapter

Cite this chapter

Bailey, D.L., Karp, J.S., Surti, S. (2005). Physics and Instrumentation in PET. In: Bailey, D.L., Townsend, D.W., Valk, P.E., Maisey, M.N. (eds) Positron Emission Tomography. Springer, London. https://doi.org/10.1007/1-84628-007-9_2

Download citation

  • DOI: https://doi.org/10.1007/1-84628-007-9_2

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-85233-798-8

  • Online ISBN: 978-1-84628-007-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics