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Chemistry of Oxygen and Its Derivatives in the Lung

  • Chapter
Hypoxic Pulmonary Vasoconstriction

Part of the book series: Developments in Cardiovascular Medicine ((DICM,volume 252))

Summary

Oxygen, reactive oxygen species, nitricoxide and reactive nitrogen species have been shown to be involved in regulating both physiological as well as pathological processes. The role oxygen and its derivatives in a living organism is dependent on the particular species formed, its concentration, location, and the presence of antioxidant machinery. Of course, oxygen is necessary in the production of energy. In addition, its derivatives play an important role in cellular signaling by acting as a molecular switch by altering ion channel activity, blood flow, and the stability of transcription factors.

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Author information

Authors and Affiliations

  1. University of Virginia, Charlottesville, Virginia, USA

    Lisa A. Palmer

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  1. Lisa A. Palmer
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Editor information

Editors and Affiliations

  1. Department of Medicine, University of California, San Diego School of Medicine, San Diego, California

    Jason X. -J. Yuan M.D., Ph.D.

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© 2004 Kluwer Academic Publishers

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Palmer, L.A. (2004). Chemistry of Oxygen and Its Derivatives in the Lung. In: Yuan, J.X.J. (eds) Hypoxic Pulmonary Vasoconstriction. Developments in Cardiovascular Medicine, vol 252. Springer, Boston, MA. https://doi.org/10.1007/1-4020-7858-7_13

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  • DOI: https://doi.org/10.1007/1-4020-7858-7_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4020-7857-6

  • Online ISBN: 978-1-4020-7858-3

  • eBook Packages: Springer Book Archive

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