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Enzymatic Systems Involved in Drug Biotransformation

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Drug Metabolism

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4.4 Final Remarks

In describing above the role and nature of enzymes in the most prominent classes, as well as some aspects of their action at the molecular level, the authors’ intention has in part been to prepare the way for an appreciation of two extremely important phenomena that govern enzyme activity and that have crucial implications for the pharmacological effects of drugs. These are the occurrence of adverse reactions and drug-drug interactions, both of which can be understood on the basis of enzyme induction and enzyme inhibition, the topics of the next chapter.

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Editors and Affiliations

  1. “I. Haţieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania

    Corina Ionescu

  2. University of Cape Town, South Africa

    Mino R. Caira

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(2005). Enzymatic Systems Involved in Drug Biotransformation. In: Ionescu, C., Caira, M.R. (eds) Drug Metabolism. Springer, Dordrecht. https://doi.org/10.1007/1-4020-4142-X_4

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