Abstract
The elaboration of highly sensitive and express methods for quantitative and qualitative detection and monitoring of chemical warfare agents (CWA), organophosphate and carbamate pesticides, compounds with delayed neurotoxicity, and pathogenic microorganisms and viruses is discussed. The application of potentiometric and amperometric biosensors, automatic biosensors discriminating the neurotoxins of different classes, is performed. The information about biosensors detecting the compounds with delayed neurotoxicity through the evaluation of “neurotoxic esterase” activity in the blood is presented. The use of immunochip technology for the detection of pathogenic microorganisms and viruses is demonstrated. The enzymatic methods of destruction of organophosphorus neurotoxins are considered as the base of new defense technology
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
J. Wang, Y. Lin, A.V. Eremenko, I.N. Kurochkin, M.F. Mineyeva Anal.Chem., 65, 513–516 (1993).
J. Wang, E. Dempsey, A. Eremenko, M. Smyth. Anal. Chim. Acta, 279, 203–208 (1993).
J. Wang J., Y. Lin, A.V. Eremenko, A.L. Gindilis, I.N. Kurochkin. Anal. Lett., 26, 197–207 (1993).
Makower, A.V. Eremenko, K. Streffer, U. Wollenberger, F.W. Scheller. J. Chem. Technol. Biotechnol., 65, 39–44 (1996).
F.F. Bier, E. Ehrentreich-Foerster, F.W. Scheller, A. Makower, A. Eremenko, U. Wollenberger, Ch.G. Bauer, D. Pfeiffer, N. Michael. Sensors & Actuators. B., 33, 5–12 (1996).
Ch.G. Bauer, A.V. Eremenko, E. Ehrentreich-Foerster, F.F. Bier, A. Makower, H.B. Halsall, W.R. Heineman, F.W. Scheller. Anal. Chem., 68, 2453–2458 (1996).
A.V. Eremenko, A. Makower, C.G. Bauer, I.N. Kurochkin, F.W. Scheller. Electroanalysis, 9, 1–5 (1997).
Makower, A. Barmin, F. Scheller. Biospektrum, 6, 119–121 (2000).
F.W. Scheller, A. Makower, F. Bier, U. Wollenberger, A. Ghindilis, A. Eremenko, D. Pfeiffer. GIT Fachz. Lab., 6, 560–561 (1995).
Makover, A. Barmin, T. Morzunova, A. Eremenko, I. Kurochkin, F. Scheller. Anal. Chim. Acta, 357, 13–20 (1997).
F.F. Bier, E. Ehrentreich-Foerster, R. Doelling, A.V. Eremenko, F.W. Scheller. Anal. Chim.Acta, 344, 119–124 (1997).
A.V. Eremenko, C.G. Bauer, A. Makower, B. Kanne, H. Baumgarten, F.W. Scheller. Anal. Chim.Acta, 358, 5–13 (1998).
C.G. Bauer, A.V. Eremenko, A. Kuehn, K. Kuerzinger, A. Makower, F.W. Scheller. Anal.Chem., 70, 4624–4630 (1998).
I.N. Kurochkin. Adv. in Biosensors, 3, 77–109 (1995).
Budashov, I. Kurochkin, A. Denisov, V. Skripnyuk, G. Shabanov. J.Microbiol.& Epidemiology (Rus.), 6, 11–15 (1997).
Kurochkin, I. Budashov, A. Pavelev, A. Denisov, V. Skripnyuk, G. Shabanov. Sensornie sistemi (Rus.), 12, 122–134 (1998).
Pavelev, I. Kurochkin, S. Chernov. Biol.Membrane(Rus.), 15, 342–348 (1998).
I.A. Budashov I.A., I.N. Kurochkin, V.V. Tsibezov, S.L. Kalnov, A.K. Denisov, O.I. Kiselyova, I.V. Yaminsky. Biol.Membranes (Rus.), 16, 325–335 (1999).
I.A. Budashov, I.N. Kurochkin, V.V. Tsibezov, S.L. Kalnov, A.K. Denisov, O.I. Kiselyova, I.V. Yaminsky. Membr.Cell Biol., 13, 397–409 (2000).
Yu.G. Zhukovskii, S.A. Kutsenko, L.P. Kuznetsova, E.E. Sochilina, E.N. Dmitrieva, M.L. Fartseiger, V.D. Tonkopii, N.N. Korkishko, V.I. Kozlovskaya, V.E. Fel’d. J.Evol.Biochem.Physiol. (Russ.) 30, 177–184 (1994).
E.N. Efremenko, V.S. Sergeeva. Russ.Chem.Bull, Int.Ed. 50, 1826–1832 (2001).
R.S. Gold, M.E. Wales, J.K. Grimsley, J.R. Wild. In “Enzymes in Action: Green Solution for Chemical Problems”, ed. B. Zwanenburg, M. Mikolajczyk, P. Kielbasinski, NATO Science Series, Vol.33, p.263–288 (2000).
V.S. Sergeeva, E.N. Efremenko, G.M. Kazankov, S.D. Varfolomeyev. J.Molec.Catalysis B: Enzymatic, 10, 571–576 (2000).
E.N. Efremenko, V.I. Lozinsky, V.S. Sergeeva, F.M. Plieva, T.A. Makhlis, G.M. Kazankov, A.K. Gladilin, S.D. Varfolomeyev. J.Biochem.Biophys.Methods, 51, 195–201 (2002).
E.I. Rainina, E.N. Efremenko, S.D. Varfolomeyev, A.L. Simonian, J.R. Wild. Biosens.Bioelectron. 11, 991–1000 (1996).
A.L. Simonian, E.N. Efremenko, J.R. Wild. Anal.Chem. Acta 444, 179–186 (2001).
A.L. Ghindilis and I.N. Kurochkin. Biosens.&Bioelectronics, 9, 353–357 (1994).
A.L. Ghindilis, T.G. Morzunova, A.V. Barmin, I.N. Kurochkin. Biosens. &Bioelectronics, 11, 873–880 (1996).
S.D. Varfolomeyev, A.Y. Yaropolov, I.N. Kurochkin. Biosens. & Bioelectronics, 11, 863–871 (1996).
L.V. Sigolaeva, A.V. Eremenko, A. Makower, G.F. Makhaeva, V.V. Malygin, I.N. Kurochkin. Chem.-Biol.Interactions, 119–120, 559–565 (1999).
L.V. Sigolaeva, A. Makower, A.V. Eremenko, G.F. Makhaeva, V.V. Malygin, I.N. Kurochkin, F.W. Scheller. Anal.Biochem., 290, 1–9 (2001).
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2005 Springer
About this paper
Cite this paper
Varfolomeyev, S., Kurochkin, I., Eremenko, A., Rainina, E., Gachok, I. (2005). Biosensors and Nanotechnological Immunochips for the Detection and Monitoring of Chemical and Biological Agents. In: Morrison, D., Milanovich, F., Ivnitski, D., Austin, T.R. (eds) Defense against Bioterror. NATO Security through Science Series. Springer, Dordrecht. https://doi.org/10.1007/1-4020-3384-2_18
Download citation
DOI: https://doi.org/10.1007/1-4020-3384-2_18
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-3386-5
Online ISBN: 978-1-4020-3384-1
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)