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Development of Biotechnology for Commiphora wightii: A Potent Source of Natural Hypolipidemic and Hypocholesterolemic Drug

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Abstract

Commiphora wightii has become an endangered species due to its overexploitation for its gum-resin. Guggulsterones present in gum-resin are potent lipid and cholesterol lowering natural agents. Drugs based on these are currently used clinically in India and Europe. The plant is endemic to Indian subcontinent, therefore major contributions on its biology, chemistry, pharmacology and biotechnology have been made by Indian scientists. Biotechnological approaches made for guggulsterone production by cell cultures and for its micropropagation are reviewed.

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  1. Laboratory of Bio-Molecular Technology, Department of Botany, M.L. Sukhadia University, Udaipur, 313001, India

    Sandeep Kumar, S.S Suri, K.C. Sonie & K.G. Ramawat

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  1. Sandeep Kumar
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  1. Faculty of Science, Centre for Biotechnology, Jamia Hamdard, New Delhi, India

    P.S. Srivastava  & Alka Narula  & 

  2. Department of Genetics, University of Delhi South Campus, New Delhi, India

    Sheela Srivastava

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Kumar, S., Suri, S., Sonie, K., Ramawat, K. (2004). Development of Biotechnology for Commiphora wightii: A Potent Source of Natural Hypolipidemic and Hypocholesterolemic Drug. In: Srivastava, P., Narula, A., Srivastava, S. (eds) Plant Biotechnology and Molecular Markers. Springer, Dordrecht. https://doi.org/10.1007/1-4020-3213-7_8

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