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The HCN World

Establishing Protein — Nucleic Acid Life via Hydrogen Cyanide Polymers

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Origins

Part of the book series: Cellular Origin, Life in Extreme Habitats and Astrobiology ((COLE,volume 6))

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7. References

  • Boonman, A.M.S., Stark, R., Van der Taak, F.F.S., van Dischoek, E.F., van der Waal, P.B., Schäfer, F., de Lange, G., and Lauwen, W.M. (2001) Highly abundant HCN in the inner hot envelope of GL 2591: Probing the birth of a hot core?, Astrophysical J. 553, L63–L67.

    Article  Google Scholar 

  • Budil, D.E., Roebber, J.L., Liebman, S.A., and Matthews, C.N. (2003) Multifrequency electron spin resonance detection of solid state organic free radicals in HCN polymers and a Titan tholin, Astrobiology, in press.

    Google Scholar 

  • Cronin, J.R. (1976) Acid-labile amino acid precursors in the Murchison meteorite, Origins of Life 7, 337–348.

    Article  CAS  Google Scholar 

  • Cronin, J.R., Pizzarello, S., and Matthews, C.N. (1993) unpublished results.

    Google Scholar 

  • Cruikshank, D.P., Hartmann, W.K., Tholen, D.J., Allamandola, L.J., Brown, R.H., Matthews, C.N., and Bell, J.F. (1991) Solid CN bearing material on outer solar system bodies, Icarus 94, 345–353.

    Article  CAS  Google Scholar 

  • Ehrenfreund, P., Boon, J.J., Commandeur, J., Sagan, C, Thompson, W.R., and Khare, B. (1994) Analytical pyrolysis experiments of Titan aerosol analogues in preparation for the Cassini-Huyghens mission, Adv. Space Res. 15(3) 335–342.

    Article  CAS  Google Scholar 

  • Evans, R.A., Lorencak, P., Ha, T.-K., and Wentrup, C. (1991) HCN dimers: iminoacetonitrile and N-cyanomethanimine, J. Am. Chem. Soc. 113, 7261.

    Article  CAS  Google Scholar 

  • Ferris, J.P., and Hagan, WJ. (1984) HCN and chemical evolution: the possible role of cyano compounds in prebiotic synthesis, Tetrahedron 40, 1093–1120.

    Article  CAS  Google Scholar 

  • Garbow, J.R., Schaefer, J., Ludicky, R.A., and Matthews, C.N. (1987) Detection of secondary amides in HCN polymers by dipolar rotational spin-echo 15N NMR, Macromolecules 20, 305–309.

    Article  CAS  Google Scholar 

  • Jameson, C.J., and Yang, W. (1972) Quantum-mechanical treatment of the electronic structures and geometry of the hydrogen cyanide dimer, J. Theor. Biol. 35,247–257.

    Article  CAS  Google Scholar 

  • Joyce, G.F., and Orgel, L.E. (1993) Prospects for understanding the origin of the RNA world in Gesteland, R.F., and Atkins, J.F. (eds) The RNA World, Cold Spring Harbor Lab Press, Ch. 1.

    Google Scholar 

  • Keller, H.U., Arpigny, C, Barbieri, C, Bonnet, R.M., Cazes, S., Coradini, M., Cosmovici, C.B., Delamere, W.A., Huebner, W.F., Hughes, D.W., Jamar, C, Malaise, D., Reitsema, H.J., Schmidt, W.K.H., Seige, P., Whipple, F.L., and Wilhelm, K. (1986) First Halley multicolour imaging results from Giotto, Nature 321, 320–326.

    Article  Google Scholar 

  • Kerridge, J.F. (1991) A note on the prebiotic synthesis of organic acids in carbonaceous meteorites, Origins of Life 21, 19–21.

    Article  CAS  Google Scholar 

  • Khare, B.N., Sagan, C, Thompson, W.R., Arakawa, E.T., Suits, F., Calcott, T.A., Williams, M.W., Shrader, S., Ogino, H., Willingham, T.O., and Nagy, B. (1984) The organic aerosols of Titan, Adv. Space Res 4, 59–68.

    Article  CAS  Google Scholar 

  • Khare, B.N., Sagan, C, Thompson, W.R., Flynn, L., and Morrison, MA. (1989) Amino acids and their polymers in the lower clouds of Jupiter? Preliminary findings, Origins of Life 19, 495–496.

    Article  Google Scholar 

  • Khare, B.N., Thompson, W.R., Sagan, C, and Arakawa, F.T. (1993) Organic aerosols in the atmosphere of Titan, Origins of Life 24, 95–96.

    Google Scholar 

  • Khare, B.N., Sagan, C., Thompson, W.R., Arakawa, E.T., Meiss, C., Tuminello, P.S. (1994) Optical properties of poly-HCN and their astronomical applications, Can. J. Chem. 72, 678–694.

    CAS  Google Scholar 

  • Kliss, R.M., and Matthews, C.N. (1962) Hydrogen cyanide dimer and chemical evolution, Proc. Natl. Acad. Sci. U.S. 48, 1300–1306.

    CAS  Google Scholar 

  • Kvenvolden, K.A., Lawless, J.G., and Folsome, C.E. (1973) Organic matter in meteorites, Sci. Amer. 227, June, 38–54.

    Google Scholar 

  • Liebman, S.A., Pesce-Rodriguez, R.A., and Matthews, C.N. (1995) Organic analysis of hydrogen cyanide polymers: prebiotic and extraterrestrial chemistry, Adv. SpaceRes. 15,(3) 71–80.

    Article  CAS  Google Scholar 

  • Lowe, C.U., Rees, M.W., and Markham, R. (1963) Synthesis of complex organic compounds from simple precursors: formation of amino acids, amino acid polymers, fatty acids and purines from ammonium cyanide, Nature 199, 219–222.

    CAS  Google Scholar 

  • Matthews, C.N., and Moser, R.E. (1966) Prebiological protein synthesis, Proc. Natl. Acad. Sci. U.S. 56, 1087–1094.

    CAS  Google Scholar 

  • Matthews, C.N., and Moser, R.E. (1967) Peptide synthesis from hydrogen cyanide and water, Nature 215, 1230–1234.

    CAS  Google Scholar 

  • Matthews, C.N., Nelson, J., Varma, P., and Minard, R.D. (1977) Deuterolysis of amino acid precursors: evidence for hydrogen cyanide polymers as protein ancestors, Science 198, 622–624.

    CAS  Google Scholar 

  • Matthews, C.N., Nelson, J.E., and Minard, R.D. (1980) Deuterolysis of amino acid precursors: evidence for hydrogen cyanide polymers as protein ancestors, Abstracts, 6th Int. Conf. on the Origins of Life, Jerusalem, June, 100.

    Google Scholar 

  • Matthews, C.N. (1982) Heteropolypeptides on Titan?, Origins of Life 12, 281–286.

    Article  CAS  Google Scholar 

  • Matthews, C.N. (1984) Chemical evolution: protons to proteins, Proc. Roy. Inst. Gt. Britain 55, 199–206.

    Google Scholar 

  • Matthews, C.N., Ludicky, R.A., Schaefer, J., Stejskal, E.O., and McKay, RA. (1984) Heteropolypeptides from hydrogen cyanide and water: solid state 15N NMR investigations, Origins of Life 14,243–249.

    Article  CAS  Google Scholar 

  • Matthews, C.N., and Ludicky, R.A. (1986) The dark nucleus of comet Halley: hydrogen cyanide polymers, Proc. 20th ESLAB Symposium on the Exploration ofHalley&s Comet, ESA SP-250, 273–277.

    Google Scholar 

  • Matthews, C.N. (1986) Simultaneous synthesis of polypeptides and polynucleotides? Hydrogen cyanide polymers as prebiotic condensing agents, Origins of Life 16, 500.

    Google Scholar 

  • Matthews, C.N. (1988) Cosmic metabolism: the origin of macromolecules, in Marx, G. (ed.), Bioastronomy-The Next Steps, Kluwer, Dordrecht, Holland, 167–178.

    Google Scholar 

  • Matthews, C.N. (1990) Simultaneous synthesis of polypeptides and polynucleotides? Hydrogen cyanide polymers as prebiotic condensing agents, in Ponnamperuma, C, and Eirich, F.R. (eds.), Prebiological Self Organization of Matter, Deepak, Hampton, VA, 171–178.

    Google Scholar 

  • Matthews, C.N. (1992) Dark matter in the solar system: hydrogen cyanide polymers, Origins of Life 21, 421–434.

    Google Scholar 

  • Matthews, C.N., and Ludicky, R.A. (1992) Hydrogen cyanide polymers on comets, Adv. Space Res 12,(4) 21–24.

    Article  CAS  Google Scholar 

  • Matthews, C.N. (1997) Hydrogen cyanide polymers from the impact of Comet P/Shoemaker/Levy 9 on Jupiter, Adv. Space Res. 19,(7) 1087–1091.

    Article  CAS  Google Scholar 

  • Matthews, C.N. (2000) Chemical evolution in a Hydrogen Cyanide World, in Margulis, L., Haselton, A., and Matthews, C.N. (eds.), Environmental Evolution, 2nd Edition, MIT Press, Cambridge, MA, Ch. 3.

    Google Scholar 

  • McDonald, G.D., Khare, B.N., Thompson, W.R., and Sagan, C. (1991) CH4/NH3/H2O spark tholin: chemical analysis and interaction with Jovian aqueous clouds, Icarus 94, 354–367.

    Article  CAS  Google Scholar 

  • McKay, R.A., Schaefer, J., Stejskal, E.O., Ludicky, R.A., and Matthews, C.N. (1984) Double-cross-polarization detection of labeled chemical bonds in HCN polymerization, Macromolecules 17, 1124–1130.

    Article  CAS  Google Scholar 

  • Miller, S.L. (1953) A production of amino acids under possible primitive earth conditions, Science 117, 528.

    CAS  Google Scholar 

  • Miller, S.L., and Urey, H.C. (1959) Organic compounds synthesis on the primitive earth, Science 130, 245–250.

    CAS  Google Scholar 

  • Miller, S.L., and Orgel, L.E. (1974) The Origins of Life on the Earth, Prentice-Hall, Englewood Cliffs, NJ.

    Google Scholar 

  • Minard, R.D., Yang, W., Varma, P., Nelson, J., and Matthews, C.N. (1975) Heteropolypeptides from poly-α-cyanoglycine and hydrogen cyanide: a model for the origin of proteins, Science 190, 387–389.

    CAS  Google Scholar 

  • Minard, R.D., Hatcher, P.G., Gormley, R.C., and Matthews, C.N. (1998) Structural investigations of hydrogen cyanide polymers. New insights using TMAH Thermochemolysis/GC-MS, Origins of Life 28, 461–473.

    Article  CAS  Google Scholar 

  • Minard, R.D., Stauffer, E., Kahle, K., and Matthews, C.N. (2000) Titan N2/CH4 tholin contains HCN polymers: evidence from TMAH Thermochemolysis/GC-MS analysis, Abstracts, Astrobiology Sci. Conf, April, 2000.

    Google Scholar 

  • Minard, R.D., Parsons, K., Johnson, A., Shields, E., Fiddler, M., Jones, A.D., and Matthews, C.N. (2002) Surface autocatalytic HCN polymerization. Evidence for glycine oligomers in (HCN)x and a water-soluble HCN hexamer, Abstracts, Astrobiology Sci. Conf, April, 2002.

    Google Scholar 

  • Moser, R.E., and Matthews, C.N. (1968) Hydrolysis of aminoacetonitrile: peptide formation, Experientia 24, 658–659.

    Article  CAS  Google Scholar 

  • Moser, R.E., Claggett, A.R., and Matthews, C.N. (1968) Peptide formation from diaminomaleonitrile (HCN tetramer) and from aminomalononitrile (HCN trimer), Tetrahedron Lett. 1599–1608.

    Google Scholar 

  • Oró, J., and Kamat, (1961) Amino acid synthesis from hydrogen cyanide under possible primitive earth conditions, Nature 190, 442–443.

    Google Scholar 

  • Oró, J., and Kimball, A.P. (1962) Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide, Arch. Biochem. Biophys. 96, 293–295.

    Article  Google Scholar 

  • Oró, J., and Lazcano-Araujo, A. (1980) The role of HCN and its derivatives in prebiotic evolution, in Vennesland, B., Conn., E.E., Knowles, C.J., Westley, J., and Wissing, F., (eds.), Cyanide in Biology, Academic Press, New York, NY, 517–541.

    Google Scholar 

  • Owen, T. (1982) Titan, Sci. Amer. 246, February, 98–109.

    Google Scholar 

  • Peltzer, E.T., Bada, J.L., Schlesinger, G., and Miller, S.L. (1984) Strecker synthesis of amino acids, Adv. Space Res. 4, 69.

    Article  CAS  Google Scholar 

  • Pendleton, Y.J., and Cruikshank, D.P. (1994) Life from the Stars?, Sky and Telescope, March, 36–42.

    Google Scholar 

  • Pesce-Rodriguez, R.A., Liebman, S.A., and Matthews, C.N. (1993) Characterization of hydrogen cyanide polymers and the Murchison meteorite: implications for prebiotic and extraterrestrial chemistry, Origins of Life 24, 123–124.

    Google Scholar 

  • Pflüger, E. (1875) Arch. ges. Phisiol. 10, 641 (see Oró and Lazcano-Araujo, 1980).

    Article  Google Scholar 

  • Ponnamperuma, C. (1989) Chemical Evolution, J. Brit. Interplanetary Soc. 161, 1005–1010.

    Google Scholar 

  • Reinhard, R. (1986) The Giotto encounter with comet Halley, Nature 321, 313–318.

    Article  Google Scholar 

  • Rettig, T.W., Tegler, S.C., Pasto, D.J., and Mumma, M.J. (1992) Comet outbursts and polymers of HCN, Ap. J. 398,293–298.

    Article  CAS  Google Scholar 

  • Sagan, C., and Khare, B.N. (1979) Tholins: organic chemistry of grains and gas, Nature 277, 102–107.

    Article  CAS  Google Scholar 

  • Sagdeev, R.Z., Blamont, J., Galeev, A.A., Moroz, V.I., Shapiro, V.D., Shevchenko, V.I., and Szegö, K. (1986) Vega spacecraft encounters with comet Halley, Nature 321, 259–262.

    Article  Google Scholar 

  • Schaefer, J., Stejskal, E.O., Jacob, G.S., and McKay, R.M. (1982) Natural abundance N15 NMR of the solids from the reaction of HCN and ammonia, Appl. Spectr. 36, 179–182.

    Article  CAS  Google Scholar 

  • Su, Y.-L., Honda, Y., Hare, P.E., and Ponnamperuma, C. (1982) Search of peptide-like materials in electric discharge experiments, Origins of Life 19, 237–238.

    Google Scholar 

  • Sun Kwok (2002) Astronomy, June.

    Google Scholar 

  • Umemoto, K., Takahashi, M, and Yokota, K. (1987) Studies on the structure of HCN oligomers, Origins of Life 17, 283–293.

    Article  CAS  Google Scholar 

  • Völker, T. (1960) Polymeric hydrogen cyanide, Angew. Chem. 72, 379–384.

    Google Scholar 

  • Warren, C.B., Minard, R.D., and Matthews, C.N. (1974) Synthesis of α-cyanoglycine N-carboxyanhydride and α cyanoglycine. J. Org Chem. 39, 3375–3378.

    Article  CAS  Google Scholar 

  • Whipple, F.L. (1974) The nature of comets, Sci. Amer. 230, February, 48–57.

    Google Scholar 

  • Woeller, F., and Ponnamperuma, C. (1969) Organic synthesis in a simulated Jovian atmosphere, Icarus 10, 386–392.

    Article  CAS  Google Scholar 

  • Yang, W., Minard, R.D., and Matthews, C.N. (1976) Azacyclopropenylidenimine: a low energy dimer of hydrogen cyanide, J. Theor. Biol. 56, 111–123.

    CAS  Google Scholar 

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Matthews, C.N. (2004). The HCN World. In: Seckbach, J. (eds) Origins. Cellular Origin, Life in Extreme Habitats and Astrobiology, vol 6. Springer, Dordrecht. https://doi.org/10.1007/1-4020-2522-X_8

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