Abstract
This chapter describes the radiation field in space and basic radiobiological mechanisms, and then concentrates on the specific biological responses resulting from exposure of biological systems to the space radiation environment. These responses include the biological effects of the heavy ions of cosmic radiation, and interactions of radiation with the other parameters of spaceflight, above all weightlessness. Comparisons are made with terrestrial findings using particle accelerators on Earth. The chapter concludes with concerns for radiation safety during human space missions and future research projects in radiation biology, particularly related to the planetary exploration program.
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References
Apáthy I, Deme S, Fehér I, Akatov YA, Reitz G, Arkhanguelski VV (2002) Dose measurements in space by the Hungarian “Pille” TLD system Radiation Measurements 135: 381–391
Beaujean R, Kopp J, Burmeister S, Petersen F, Reitz G (2002) Dosimetry inside MIR station using a silicon detector telescope (DOSTEL). Radiation Measurements 135: 433–438
Bücker H (1975) Biostack, a study of the biological effects of HZE galactic cosmic radiation. In: Biomedical Results of Apollo. RS Johnston, LF Dietlein, CA Berry (eds) NASA SP-368, pp 343–354
Bücker H, Horneck G (1975) Studies on the effects of cosmic HZE particles on different biological systems in the Biostack expriments I and II flown onboard of Apollo 16 and 17. In: Radiation Research. OF Nygaard, HI Adler, WK Sinclair (eds) Academic Press, New York, pp 1138–1151
Casolino M, Bidoli V, Morselli A, Narici L et al. (2003) Dual origins of light flashes seen in space. Nature 422: 680
Clément G (2005) Fundamentals of Space Medicine. Kluwer Academic Publishers, Dordrecht
Cucinotta FA, Wu H, Shavers MR, George K (2003) Radiation dosimetry and biophysical models of space radiation effects. Gravitational and Space Biology Bulletin 16: 11–18
De Angelis G, Clowdsley MS, Nealy JE, Tripathi RK, Wilson JW (2004) Radiation analysis for manned missions to the Jupiter system. Adv Space Res 34: 1395– 1403
Facius R, Bücker H, Hildebrand D, Horneck G, Höltz G, Reitz G, Schäfer M, Toth B (1978) Radiobiological results from the Bacillus subtilis Biostack experiments within the Apollo and the ASTP spaceflights. Life Sci Space Res 16: 151–156
Facius R, Reitz G, Schäfer M (1994) Inactivation of individual Bacillus subtilis spores in dependence of their distance to single cosmic heavy ions. Adv Space Res 14: 1027–1038
Hinghofer-Szalkay H (1996) Physiology of cardiovascular, respiratory, interstitial, endocrine, immune and muscular systems. In: Biological and Medical Research in Space. D Moore, P Bie, H Oser (eds) Springer, Berlin, pp 107– 153
Horneck G (1992) Radiobiological experiments in space: A review. Nuclear Tracks Radiation Measurements 20: 185–205
Horneck G (1998) Biological monitoring of radiation exposure. Adv Space Res 22: 1631–1641
Horneck G (1999) Impact of microgravity on radiobiological processes and efficiency of DNA repair. Mutation Research 430: 221–228
Horneck G, Baumstark-Khan C (eds) (2002) Astrobiology, the Quest for the Conditions of Life. Springer, Berlin
Horneck G, Facius R, Reichert M, Rettberg P et al. (2003a) HUMEX, a Study on the Survivability and Adaptation of Humans to Long-Duration Exploratory Missions. European Space Agency, Noordwijk, ESA SP-1264
Horneck G, Facius R, Reichert M, Rettberg P et al. (2003b) HUMEX, a study on the survivability and adaptation of humans to long-duration exploratory missions. Part I: Lunar missions. Adv Space Res 31: 2389–2401
Horneck G, Facius R, Reichert M, Rettberg P et al. (2005) HUMEX, a study on the survivability and adaptation of humans to long-duration exploratory missions. Part II: Missions to Mars. Adv Space Res, in press
Kiefer J, Schenk-Meuser K, Kost M (1996) Radiation biology. In: Biological and Medical Research in Space. D Moore, P Bie, H Oser (eds) Springer, Berlin, pp 300–367
McCormack PD, Swenberg CE, Bücker H (eds) (1988) Terrestrial Space Radiation and its Biological Effects. Plenum Press, New York, published in cooperation with NATO Scientific Affairs Division
Mileikowsky C, Cucinotta F, Wilson JW, Gladman B et al. (2000), Natural transfer of viable microbes in space. Part 1: From Mars to Earth and Earth to Mars. Icarus 145: 391–427
Moore D, Cogoli A (1996) Gravitational and space biology at the cellular level. In: Biological and Medical Research in Space. D Moore, P Bie, H Oser (eds) Springer, Berlin, pp 1–106
NCRP (1989) Guidance on Radiation Received in Space Activities. NCRP Report No. 98. National Council on Radiation Protection and Measurements, Bethesda, MD
NCRP (2000) Radiation Protection Guidance for Activities in Low-Earth Orbit. NCRP Report No. 132. National Council on Radiation Protection and Measurements, Bethesda, MD
Nicholson WL, Munakata N, Horneck G, Melosh HJ, Setlow P (2000) Resistance of Bacillus endospores to extreme terrestrial and extraterrestrial environments. Microb Mol Biol Rev 64: 548–572
Obe G, Johannes I, Johannes C, Hallmann K, Reitz G, and Facius R (1997) Chromosomal aberrations in blood lymphocytes of astronauts after long-term space flights. Int J Radiat Biol 72: 726–734
Philpott DE, Corbett R, Turnbill C, Black S et al. (1980) Retinal changes in rats flown on Cosmos 936: A cosmic ray experiment. Aviat Space Environ Med 51: 556–562
Reitz G (1994) Space radiation dosimetry. Acta Astronautica 32: 715–722
Reitz G, Facius R, Sandler H (1995) Radiation protection in space. Acta Astronautica 35: 313–338
Reitz G, Berger T (2005) The MATROSHKA Facility - Dose determination during an EVA. Radiation Protection Dosimetry (in press)
Swenberg CE, Horneck G, Stassinopoulos EG (eds) (1993) Biological Effects and Physics of Solar and Galactic Cosmic Radiation. NATO ASI Series A: Life Sciences Vol 243 A and B. Plenum, New York
Weisbrod U, Bücker H, Horneck G, Kraft G (1992) Heavy ion effects on bacterial spores: The impact parameters dependence of the inactivation. Radiation Research 129: 250–257
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Horneck, G., Baumstark-Khan, C., Facius, R. (2006). Radiation Biology. In: Clément, G., Slenzka, K. (eds) Fundamentals of Space Biology. THE SPACE TECHNOLOGY LIBRARY, vol 18. Springer, New York, NY. https://doi.org/10.1007/0-387-37940-1_7
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DOI: https://doi.org/10.1007/0-387-37940-1_7
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