Abstract
A recent series of publications demonstrated that identification of genomic regions subjected to positive selection (hitchhiking mapping) is possible and could be applied in an ecological context. This review focuses on the use of microsatellite markers in genome scans for the identification of beneficial mutations. The pitfalls and potential of the lnR6 test statistic are discussed as well as different approaches for the identification of the molecular change(s) underlying an observed selective sweep.
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© 2006 Landes Bioscience and Springer Science+Business Media
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Schlötterer, C. (2006). Hitchhiking Mapping. In: Discovering Biomolecular Mechanisms with Computational Biology. Molecular Biology Intelligence Unit. Springer, Boston, MA. https://doi.org/10.1007/0-387-36747-0_10
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DOI: https://doi.org/10.1007/0-387-36747-0_10
Publisher Name: Springer, Boston, MA
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