BK Virus Infection after Non-Renal Transplantation

  • Martha Pavlakis
  • Abdolreza Haririan
  • David K. Klassen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 577)


Infection with BK virus (BKV), a member of the Polyomavirus (PV) family, is ubiquitous, with the virus remaining in a latent form in the kidney and urinary tract.1, 2 This infection is usually asymptomatic, but with impairment of the cellular immune system the virus can reactivate and lead to tissue damage. In recipients of bone marrow and solid organ transplants, PV reactivation can be associated with disease in urinary tract and kidneys. BKV was first discovered in 1971 from the urine of a kidney transplant recipient who had developed ureteral stenosis 4 months after transplantation. While much of the subsequent research focuses on patients after renal transplantation, we will review PV impact in patients after bone marrow transplant (BMT) and those with non-renal solid organ transplants.


Bone Marrow Transplant Solid Organ Transplant Hemorrhagic Cystitis Solid Organ Transplant Recipient Native Kidney 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© and Springer Science+Business Media 2006

Authors and Affiliations

  • Martha Pavlakis
    • 1
  • Abdolreza Haririan
    • 2
  • David K. Klassen
    • 3
  1. 1.Beth Israel Deaconess HospitalBostonUSA
  2. 2.Wayne State UniversityDetroitUSA
  3. 3.University of Maryland School of MedicineBaltimoreUSA

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