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Significance of Reverse Signal Transduction for the Biology of the CD137 Receptor/Ligand System

  • Herbert Schwarz

Abstract

CD137 is a member of the TNF receptor family and it has originally been identified as a potent T cell costimulatory molecule. Recently, it has become evident that CD137 signals can also inhibit T cell activity under certain conditions.

Keywords

CD137 Ligand Soluble CD137 Follicular Dendritic Cell Activation Induce Cell Death Tumor Necrosis Factor Family 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer 2006

Authors and Affiliations

  • Herbert Schwarz
    • 1
  1. 1.Department of PhysiologyNational University of SingaporeSingapore

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