Advertisement

Responses of the SVZ to Hypoxia and Hypoxia/Ischemia

  • Ryan J. Felling
  • H. VanGuider
  • Michael J. Romanko
  • Steven W. Levison

Keywords

Neural Stem Cell Middle Cerebral Artery Occlusion Focal Cerebral Ischemia Chronic Hypoxia Subventricular Zone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Arvidsson, A., Collin, T., Kirik, D., Kokaia Z., and Lindvall, O. (2002). Neuronal replacement from endogenous precursors in the adult brain after stroke. Nat. Med. 8: 963–970.PubMedCrossRefGoogle Scholar
  2. American Heart Association (2002). Heart Disease and Stroke Statistics — (2003) Update.Google Scholar
  3. Back, S.A., Han, B.H., Luo, N.L., Chricton, C.A., Xanthoudakis, S., Tam, J., Arvin K.L., and Holtzman, D.M. (2002). Selective vulnerability of late oligodendrocyte progenitors to hypoxia-ischemia. J. Neurosci. 22: 455–463.PubMedGoogle Scholar
  4. Back, S.A., Luo, N.L., Borenstein, N.S., Levine, J.M., Volpe, J.J., and Kinney, H.C. (2001). Late oligodendrocyte progenitors coincide with the developmental window of vulnerability for human perinatal white matter injury. J. Neurosci. 21: 1302–1312.PubMedGoogle Scholar
  5. Blakemore, W.F. (1969). The ultrastructure of the subependymal plate in the rat. J. Anat. 104: 423–433.PubMedGoogle Scholar
  6. Blomgren, K., Zhu, C., Wang, X., Karlsson, J.O., Leverin, A.L., Bahr, B.A., Mallard, C., and Hagberg, H. (2001). Synergistic activation of caspase-3 by m-calpain after neonatal hypoxia-ischemia: a mechanism of ‘pathological apoptosis’? J. Biol. Chem. 276: 10191–10198.PubMedCrossRefGoogle Scholar
  7. Brazel, C.Y. (2003). Neural stem cells are resistant to apoptosis. Doctoral Dissertation in Cell and Molecular Biology. Hershey, Pennsylvania State University, p. 186.Google Scholar
  8. Cai, Z., Sigrest, T., Hersey, K., and Rhodes, P.G. (1995). Intrauterine hypoxia-ischemia increases N-methyl-D-aspartate-induced cGMP formation and glutamate accumulation in cultured rat cerebellar granule cells. Pediatr. Res. 38: 107–112.PubMedGoogle Scholar
  9. Cammermeyer, J. (1965). The hypependymal microglia cell. Z. Anat. Entwicklungsgesch 124: 543–561.PubMedCrossRefGoogle Scholar
  10. Cheng, Y., Deshmukh, M., D’Costa, A., Demaro, J.A., Gidday, J.M., Shah, A., Sun, Y., Jacquin, M.F., Johnson E.M., and Holtzman, D.M. (1998). Caspase inhibitor affords neuroprotection with delayed administration in a rat model of neonatal hypoxicischemic brain injury [see comments]. J. Clin. Invest. 101: 1992–1999.PubMedCrossRefGoogle Scholar
  11. Chiasson, B.J., Tropepe, V., Morshead, C.M., and van der Kooy, D. (1999). Adult mammalian forebrain ependymal and subependymal cells demonstrate proliferative potential, but only subependymal cells have neural stem cell characteristics. J. Neurosci. 19: 4462–4471.PubMedGoogle Scholar
  12. Doetsch, F., Garcia-Verdugo, J.M., and Alvarez-Buylla, A. (1997). Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. J. Neurosci. 17: 5046–5061.PubMedGoogle Scholar
  13. du Plessis, A.J. and Volpe, J.J. (2002). Perinatal brain injury in the preterm and term newborn. Curr. Opin. Neurol. 15: 151–157.PubMedCrossRefGoogle Scholar
  14. Felling, R.J. and Levison, S.W. (2003). Enhanced Neurogenesis Following Stroke. J. Neurosci. Res. 73: 277–283.PubMedCrossRefGoogle Scholar
  15. Felling, R.J. (2005). A regenerative response of endogenous neural stem cells to perinatal hypoxic/ischemic brain damage. Doctoral Dissertation in Neuroscience. Hershey, Pennsylvania State University.Google Scholar
  16. Ganat, Y., Soni, S., Chacon, M., Schwartz, M.L., and Vaccarino, F.M. (2002). Chronic hypoxia up-regulates fibroblast growth factor ligands in the perinatal brain and induces fibroblast growth factor-responsive radial glial cells in the subependymal zone. Neuroscience 112: 977–991.PubMedCrossRefGoogle Scholar
  17. Garcia-Verdugo, J.M., Doetsch, F., Wichterle, H., Lim, D.A., and Alvarez-Buylla, A. (1998). Architecture and cell types of the adult subventricular zone: in search of the stem cells. J. Neurobiol. 36: 234–248.PubMedCrossRefGoogle Scholar
  18. Gill, R., Soriano, M., Blomgren, K., Hagberg, H., Wybrecht, R., Miss, M.T., Hoefer, S., Adam, G., Niederhauser, O., Kemp, J.A., and Loetscher, H. (2002). Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain. J. Cereb. Blood Flow Metab. 22: 420–430.PubMedCrossRefGoogle Scholar
  19. Hu, B.R., Liu, C.L., Ouyang, Y., Blomgren, K., and Siesjo, B.K., (2000). Involvement of caspase-3 in cell death after hypoxia-ischemia declines during brain maturation. J. Cereb. Blood Flow Metab. 20: 1294–1300.PubMedCrossRefGoogle Scholar
  20. Jin, K., Mao, X.O., Sun, Y., Xie, L., and Greenberg, D.A. (2002a). Stem cell factor stimulates neurogenesis in vitro and in vivo. J. Clin. Invest. 110: 311–329.PubMedCrossRefGoogle Scholar
  21. Jin, K., Mao, X.O., Sun, Y., Xie, L., Jin, L., Nishi, E., Klagsbrun, M., and Greenberg, D.A. (2002b). Heparin-binding epidermal growth factor-like growth factor: Hypoxia-inducible expression in vitro and stimulation of neurogenesis in vitro and in vivo. J. Neurosci. 22: 5365–5373.PubMedGoogle Scholar
  22. Jin, K., Minami, M., Lan, J.Q., Mao, X.O., Batteur, S., Simon, R.P., and Greenberg, D.A. (2001). Neurogenesisindentatesubgranularzoneandrostralsubventricularzoneafter focal cerebral ischemia in the rat. Proc. Natl. Acad. Sci. U. S. A. 98: 4710–4715.PubMedCrossRefGoogle Scholar
  23. Levison, S.W., Chuang, C., Abramson, B.J., and Goldman, J.E. (1993). The migrational patterns and developmental fates of glial precursors in the rat subventricular zone are temporally regulated. Development 119:611–622.PubMedGoogle Scholar
  24. Levison, S.W., Rothstein, R.P., Romanko, M.J., Snyder, M.J., Meyers R.L., and Vannucci, S.J. (2001). Hypoxia/ischemia depletes the rat perinatal subventricular zone of oligodendrocyte progenitors and neural stem cells. Dev. Neurosci. 23: 234–247.PubMedCrossRefGoogle Scholar
  25. Levison, S.W., Young G.M., and Goldman, J.E. (1999). Cycling cells in the neocortex preferentially generate oligodendroglia. J. Neurosci. Res. 57: 435–447.PubMedCrossRefGoogle Scholar
  26. Li, Y. and Chopp, M. (1999). Temporal profile of nestin expression after focal cerebral ischemia in adult rat. Brain Res. 838: 1–10.PubMedCrossRefGoogle Scholar
  27. Li, Z., Wang, Y., Song, J., Kataoka, H., Yoshii, S., Gao, C., Zhou, J., Ota, S., Tanaka M., and Sugimura, H. (2002). Genomic structure of the human beta-PIX gene and its alteration in gastric cancer. Cancer Lett. 177: 203–208.PubMedCrossRefGoogle Scholar
  28. Longa, E.Z., Weinstein, P.R., Carlson S., and Cummins, R. (1989). Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 20: 84–91.PubMedGoogle Scholar
  29. Mandai, K., Matsumoto, M., Kitagawa, K., Matsushita, K., Ohtsuki, T., Mabuchi, T., Colman, D.R., Kamada, T., and Yanagihara, T. (1997). Ischemic damage and subsequent proliferation of oligodendrocytes in focal cerebral ischemia. Neuroscience 77: 849–861.PubMedCrossRefGoogle Scholar
  30. Martin, L.J., Al-Abdulla, N.A., Brambrink, A.M., Kirsch, J.R., Sieber, F.E., and Portera-Cailliau, C. (1998). Neurodegeneration in excitotoxicity, global cerebral ischemia, and target deprivation: A perspective on the contributions of apoptosis and necrosis. Brain Res. Bull. 46: 281–309.PubMedCrossRefGoogle Scholar
  31. Ment, L.R., Schwartz, M., Makuch, R.W., and Stewart, W.B. (1998). Association of chronic sublethal hypoxia with ventriculomegaly in the developing rat brain. Brain Res. Dev. Brain Res. 111: 197–203.PubMedCrossRefGoogle Scholar
  32. Nakatomi, H., Kuriu, T., Okabe, S., Yamamoto, S., Hatano, O., Kawahara, N., Tamura, A., Kirino, T., and Nakafuku, M. (2002). Regeneration of hippocampal pyramidal neurons after ischemic brain injury by recruitment of endogenous neural progenitors. Cell 110: 429–441.PubMedCrossRefGoogle Scholar
  33. Ness, J.K., Romanko, M.J., Rothstein, R.P., Wood, T.L., and Levison, S.W. (2001). Perinatal hypoxia-ischemia induces apoptotic and excitotoxic death of periventricular white matter oligodendrocyte progenitors. Dev. Neurosci. 23: 203–208.PubMedCrossRefGoogle Scholar
  34. Northington, F.J., Ferriero, D.M., Flock, D.L., and Martin, L.J. (2001). Delayed neurodegeneration in neonatal rat thalamus after hypoxia-ischemia is apoptosis. J. Neurosci. 21: 1931–1938.PubMedGoogle Scholar
  35. Parent, J.M., Vexler, Z.S., Gong, C., Derugin, N., and Ferriero, D.M. (2002). Rat forebrain neurogenesis and striatal neuron replacement after focal stroke. Ann. Neurol. 52: 802–813.PubMedCrossRefGoogle Scholar
  36. Puka-Sundvall, M., Hallin, U., Zhu, C., Wang, X., Karlsson, J.O., Blomgren, K., and Hagberg, H. (2000). NMDA blockade attenuates caspase-3 activation and DNA fragmentation after neonatal hypoxia-ischemia. Neuroreport 11: 2833–2836.PubMedGoogle Scholar
  37. Puka-Sundvall, M., Sandberg, M., and Hagberg, H. (1997). Brain injury after hypoxia-ischemia in newborn rats: relationship to extracellular levels of excitatory amino acids and cysteine. Brain Res. 750: 325–328.PubMedCrossRefGoogle Scholar
  38. Rice, J.E., Vannucci, R.C., and Brierley, J.B. (1981). The influence of immaturity on hypoxic-ischemic brain damage in the rat. Ann. Neurol. 9: 131–141.PubMedCrossRefGoogle Scholar
  39. Romanko, M.J. (2004). Vulnerability of the stem/progenitor cells in the newborn subependymal zone to hypoxia/ischemia. Doctoral Dissertation in Molecular Medicine. Hershey, Pennsylvania State University. PhD.Google Scholar
  40. Romanko, M.J., Rothstein, R.P., and Levison, S.W. (2004). Neural Stem Cells in the Subventricular Zone are Resistant to Cell Death Subsequent to Perinatal Hypoxia-Ischemia. J. Cereb. Blood Flow Met. 24: 814–825.CrossRefGoogle Scholar
  41. Rothstein, R.P. and Levison, S.W. (2002). Damage to the choroid plexus, ependyma and subependyma as a consequence of perinatal hypoxia/ischemia. Dev. Neurosci. 24: 426–436.PubMedCrossRefGoogle Scholar
  42. Sato, K., Hayashi, T., Sasaki, C., Iwai, M., Li, F., Manabe, Y., Seki, T., and Abe, K. (2001). Temporal and spatial differences of PSA-NCAM expression between young-adult and aged rats in normal and ischemic brains. Brain Res. 922: 135–139.PubMedCrossRefGoogle Scholar
  43. Shimizu, N.M., Ishi, Y. (1957). Histochemical studies of succinic dehydrogenase and cytochrome oxidase of the rabbit brain, with special reference to the results in the paraventricular structures. J. Comp. Neurol. 108: 1–21.PubMedCrossRefGoogle Scholar
  44. Shingo, T., Sorokan, S.T., Shimazaki, T., and Weiss, S. (2001). Erythropoietin regulates the in vitro and in vivo production of neuronal progenitors by mammalian forebrain neural stem cells. J. Neurosci. 21: 9733–9743.PubMedGoogle Scholar
  45. Skoff, R.P., Bessert, D.A., Barks, J.D., Song, D., Cerghet, M., and Silverstein, F.S. (2001). Hypoxic-ischemic injury results in acute disruption of myelin gene expression and death of oligodendroglial precursors in neonatal mice. Int. J. Dev. Neurosci. 19: 197–208.PubMedCrossRefGoogle Scholar
  46. Smith, M.L., Bendek, G., Dahlgren, N., Rosen, I., Wieloch, T., and Siesjo, B.K. (1984). Models for studying long-term recovery following forebrain ischemia in the rat. 2. A 2-vessel occlusion model. Acta Neurol. Scand. 69: 385–401.PubMedCrossRefGoogle Scholar
  47. Stewart, W.B., Ment, L.R., and Schwartz, M. (1997). Chronic postnatal hypoxia increases the numbers of cortical neurons. Brain Res. 760: 17–21.PubMedCrossRefGoogle Scholar
  48. Stoll, G., Jander, S., and Schroeter, M. (1998). Inflammation and glial responses in ischemic brain lesions. Prog. Neurobiol. 56: 149–171.PubMedCrossRefGoogle Scholar
  49. Studer, L., Csete, M., Lee, S.H., Kabbani, N., Walikonis, J., Wold, B., and McKay, R. (2000). Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J. Neurosci. 20: 7377–7383.PubMedGoogle Scholar
  50. Szele, F.G., Dowling, J.J., Gonzales, C., Theveniau, M., Rougon, G., and Chesselet, M.F. (1994). Pattern of expression of highly polysialylated neural cell adhesion molecule in the developing and adult rat striatum. Neuroscience 60: 133–144.PubMedCrossRefGoogle Scholar
  51. Tanaka, K., Nogawa, S., Ito, D., Suzuki, S., Dembo, T., Kosakai, A., and Fukuuchi, Y. (2001). Activation of NG2-positive oligodendrocyte progenitor cells during post-ischemic reperfusion in the rat brain. Neuroreport 12: 2169–2174.PubMedCrossRefGoogle Scholar
  52. Towbin, A. (1998). Brain Damage in the Newborn and its Neurologic Sequels: Pathological and Clinical Correlation. PRM Publishing Company, Inc., Danvers, MA.Google Scholar
  53. Vannucci, S.J., Seaman, L.B., and Vannucci, R.C. (1996). Effects of hypoxia-ischemia on GLUT1 and GLUT3 glucose transporters in immature rat brain. J. Cereb. Blood Flow and Met. 16: 77–81.CrossRefGoogle Scholar
  54. Volpe, J.J. (2001). Neurobiology of periventricular leukomalacia in the premature infant. Pediatr. Res. 50: 553–562.PubMedGoogle Scholar
  55. Wang, X., Karlsson, J.O., Zhu, C., Bahr, B.A., Hagberg, H., and Blomgren, K., 2001. Caspase-3 activation after neonatal rat cerebral hypoxia-ischemia. Biol. Neonate. 79: 172–179.PubMedCrossRefGoogle Scholar
  56. Zhang, R., Zhang, Z., Wang, L., Wang, Y., Gousev, A., Zhang, L., Ho, K.L., Morshead, C., and Chopp, M. (2004). Activated neural stem cells contribute to stroke-induced neurogenesis and neuroblast migration toward the infarct boundary in adult rats. J. Cereb. Blood Flow Metab. 24: 441–448.PubMedCrossRefGoogle Scholar
  57. Zhang, R.L., Zhang, Z.G., Zhang, L., and Chopp, M. (2001). Proliferation and differentiation of progenitor cells in the cortex and the subventricular zone in the adult rat after focal cerebral ischemia. Neuroscience 105: 33–41.PubMedCrossRefGoogle Scholar
  58. Zhu, C., Wang, X., Hagberg, H., and Blomgren, K. (2000). Correlation between caspase-3 activation and three different markers of DNA damage in neonatal cerebral hypoxia-ischemia. J. Neurochem. 75: 819–829.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Ryan J. Felling
    • 1
  • H. VanGuider
    • 1
  • Michael J. Romanko
    • 1
  • Steven W. Levison
    • 2
    • 3
  1. 1.Department of Neurology and NeuroscienceUMDNJ-New Jersey Medical SchoolNewark
  2. 2.Department of Neural and Behavioral SciencesPennsylvania State University College of MedicineHershey
  3. 3.Department of Neurology and NeuroscienceUMDNJ-New Jersey Medical SchoolNewark

Personalised recommendations