Perchlorate pp 297-310 | Cite as

The Biochemistry and Genetics of Microbial Perchlorate Reduction

  • Laurie A. Achenbach
  • Kelly S. Bender
  • Yvonne Sun
  • John D. Coates


The identification and analysis of the genes encoding perchlorate reductase and chlorite dismutase has provided not only a building block for pathway understanding, but has also provided a tool for bioremediative and phylogenetic studies. On-going genome sequencing will further facilitate transcriptional profiling under perchlorate-reducing conditions via microarray analyses. This analysis will give a more inclusive look into transcriptional expression patterns associated with the perchlorate metabolism. While further advancements in the genetic analysis of perchlorate-reducing bacteria continue, the recent development of a genetic system in D. aromatica will provide an invaluable tool for corroborating microarray results and solidifying hypotheses regarding microbial perchlorate metabolism.


Transposase Gene Perchlorate Reduction Chlorate Reduction Chlorite Dismutase Nest Polymerase Chain Reaction Approach 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Laurie A. Achenbach
    • 1
  • Kelly S. Bender
    • 2
  • Yvonne Sun
    • 3
  • John D. Coates
    • 3
  1. 1.Southern Illinois UniversityCarbondale
  2. 2.BioInsite, LLCCarbondale
  3. 3.University of California-BerkeleyBerkeley

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