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Alteration of Brain Oxygenation During “Piggy Back” Liver Transplantation

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Oxygen Transport to Tissue XXVII

5. Conclusion

Relevant changes in cerebral circulation occur during “Piggy Back” liver transplantation. Particularly at the washout-reperfusion time the cerebral perfusion suddenly changes from its lowest to its highest values. Further investigation is required to evaluate whether patients with the greatest change in cerebral oxygenation at this time point will suffer neurological complications after transplantation.

It is remarkable that TOI and THI levels are higher in the most compromised patients, perhaps because of an increased CO and, mainly, because of a decreased vascular resistance.

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Panzera, P. et al. (2006). Alteration of Brain Oxygenation During “Piggy Back” Liver Transplantation. In: Cicco, G., Bruley, D.F., Ferrari, M., Harrison, D.K. (eds) Oxygen Transport to Tissue XXVII. Advances in Experimental Medicine and Biology, vol 578. Springer, Boston, MA . https://doi.org/10.1007/0-387-29540-2_43

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