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Assaying ATP Synthase Rotor Activity

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Part of the Advances in Experimental Medicine and Biology book series (volume 578)

6. Conclusions

With the development of laser excitation and detection systems, it has become possible to consider analyses that have otherwise been beyond the capacity of experimentalists. In this investigation, a case is made for the development of a device to analyse ATP synthase activity in-vivo. Such analyses ultimately have applications in clinical practice, particularly in the field of mitochondrial disorders, of both nuclear and mitochondrial DNA origin.

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Maguire, D., Shah, J., McCabe, M. (2006). Assaying ATP Synthase Rotor Activity. In: Cicco, G., Bruley, D.F., Ferrari, M., Harrison, D.K. (eds) Oxygen Transport to Tissue XXVII. Advances in Experimental Medicine and Biology, vol 578. Springer, Boston, MA . https://doi.org/10.1007/0-387-29540-2_11

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