Abstract
Suppose that we wanted to obtain a sample of DNA that contained a specific gene or portion of a gene with very little other DNA. How could we do this? Today, given a genome sequence, we could design PCR primers flanking the DNA of interest and by PCR could amplify just that segment. Prior to the development of rapid genomic sequencing technologies, the process was much more complicated.
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References
Galas DJ, Eggert M, Waterman MS (1985) Rigorous pattern-recognition methods for DNA sequences. Journal of Molecular Biology 186:117–128.
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© 2005 Springer Science+Business Media, Inc.
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(2005). Word Distributions and Occurrences. In: Computational Genome Analysis. Springer, New York, NY. https://doi.org/10.1007/0-387-28807-4_3
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DOI: https://doi.org/10.1007/0-387-28807-4_3
Publisher Name: Springer, New York, NY
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