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Finding Disease-Causing Genes

Abstract

Among the 4000 known human genetic disorders, only a handful of disease-causing genes have been mapped. To locate a gene (say an average of 10,000 bp length) in the midst of a 3.2 billion bp chromosomal DNA is hardly a simple task.

Keywords

Splice Site Variable Number Tandem Repeat Yeast Artificial Chromosome Chromosome Walking Exon Splice Site 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Chapter 17: Finding Disease-Causing Genes

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© Springer Science+Business Media, Inc. 2006

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