Advertisement

Structure and Function of a Viral Encoded K+ Channel

  • Anna Moroni
  • James Van Etten
  • Gerhard Thiel
Part of the Protein Reviews book series (PRON, volume 1)

Keywords

Influenza Virus Xenopus Oocyte Channel Protein Selectivity Filter Host Plasma Membrane 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Barhanin, J., Lesage, F., Guillemare, E., Fink, M., Lazdunski, M., and Romey, G. (1996). K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current. Nature 384, 78–80.PubMedCrossRefGoogle Scholar
  2. Blanpied, T.A., Boeckman, F.A., Aizenman, E., and Johnson, J.W. (1997). Trapping channel block of NMDA-activated responses by amantadine and memantine. J. Neurophysiol. 77, 309–323.PubMedGoogle Scholar
  3. Blatt, M.R. and Thiel, G. (1993). Hormonal control of ion channel gating. Annu. Rev. Plant Mol. Physiol. 44, 543–567.CrossRefGoogle Scholar
  4. Boulanger, P. and Letellier, L. (1988). Characterization of ion channels involved in the penetration of phage T4 DNA into Escherichia coli cells. J. Biol. Chem. 15, 9767–9775.Google Scholar
  5. Bronner, C. and Landry, Y. (1991). The use of the potential-sensitive fluorescent probe bisoxonol in mast cells. Biochim. Biophys. Acta. 1070, 321–331.PubMedCrossRefGoogle Scholar
  6. Carrasco, L. (1995). Modification of membrane permeability by animal viruses. Adv. Virus Res. 45, 61–112.PubMedGoogle Scholar
  7. Chase, T.E., Nelson, J.A., Burbank, D.E., and Van Etten, J.L. (1989). Mutual exclusion occurs in a chlorella-like green alga inoculated with two viruses. J. Gen. Virol. 70, 1829–1836.PubMedCrossRefGoogle Scholar
  8. Ciampor, F., Cmark, D., Cmarkova, J., and Zavodska, E. (1995). Influenza virus M2 protein and haemagglutinin conformation changes during intracellular transport. Acta Virol. 39, 171–181.PubMedGoogle Scholar
  9. Coady, M.J., Daniel, N.G., Tiganos, E., Allain, B., Friborg, J., Lapointe, J.Y. et al. (1998). Effects of Vpu expression on Xenopus oocyte membrane conductance. Virology 244, 39–49.PubMedCrossRefGoogle Scholar
  10. Cortes, D.M., Cuello, L.G., and Perozo, E. (2001). Molecular architecture of a full-length Kcs: Role of cytoplasmic domains in ion permeation and activation gating. J. Gen. Physiol. 117, 165–180.PubMedCrossRefGoogle Scholar
  11. Daugelavicius, R., Bamford, J.K.H., and Bamford, D.H. (1997). Changes in host cell energetics in response to bacteriophage PRD1 DNA entry. J. Bacteriol. 179, 5203–5210.PubMedGoogle Scholar
  12. DeBoer, A.H. (2002). Plant 14-3-3 proteins assist ion channels and pumps. Biochem. Soc. Trans. 30, 416–421.CrossRefGoogle Scholar
  13. Delaroque, N., Muller, D.G., Bothe, G., Pohl, T., Knippers, R., and Boland, W. (2001). The complete DNA sequence of the Ectocarpus siliculosus virus Es V-1 genome. Virology 15, 112–132.CrossRefGoogle Scholar
  14. Derst, C. and Karschin, A. (1998). Evolutionary link between prokaryotic and eukaryotic K+ channels. J. Exp. Biol. 201, 2791–2799.Google Scholar
  15. Doyle, D.A., Cabral, J.M., Pfuetzner, R.A., Kuo, A., Gulbis, J.M., Cohen, S.L., et al. (1998). The structure of the potassium channel: Molecular basis of K+ conduction and selectivity. Science 280, 69–76.PubMedCrossRefGoogle Scholar
  16. Fischer, W.B. and Sansom, M.S. (2002). Viral ion channels: Structure and function. Biochim. Biophys. Acta 1561, 27–45.PubMedCrossRefGoogle Scholar
  17. Garcia, M.L., Garcia-Calvo, M., Hidalgo, P., Lee, A., and MacKinnon, R. (1994). Purification and characterization of three inhibitors of voltage-dependent K+ channels from Leiurus quinquestriatus var. hebraeus venom. Biochemistry 33, 6834–6839.PubMedCrossRefGoogle Scholar
  18. Gazzarrini, S., Van Etten, J.L., DiFrancesco, D., Thiel, G., and Moroni, A. (2002). Voltage-dependence of virusencoded miniature K+ channel Kcv. J. Memb. Biol. 187, 15–25.CrossRefGoogle Scholar
  19. Gazzarrini, S., Severino, M., Lombardi, M., Morandi, M., DiFrancesco, D., Van Etten, J.L. et al. (2003). The viral potassium channel Kcv: Structural and functional features. FEBS Lett. 552, 12–16.PubMedCrossRefGoogle Scholar
  20. Gonzalez, M.E. and Carrasco, L. (2003). Viroporins. FEBS Lett. 552, 28–34.PubMedCrossRefGoogle Scholar
  21. Griffin, S.D., L.P. Beales, D.S. Clark, O. Worsfold, S.D. Evans, J. Jaeger, et al. (2003). FEBS Lett. 535, 34–38.PubMedCrossRefGoogle Scholar
  22. Heginbotham, L., Lu, Z., Abramson, T., and MacKinnon, R. (1994). Mutations in the K+ channel signature sequence. Biophys. J. 66, 1061–1067.PubMedCrossRefGoogle Scholar
  23. Hille, B. (2001). Ion Channels of Excitable Membranes, 3nd edn. Sinauer Associates Inc., Sunderland, MA.Google Scholar
  24. Jiang, Y., Lee, A., Chen, J., Cadene, M., Chait, B.T., and MacKinnon, R. (2002). Crystal structure and mechanism of a calcium-gated potassium channel. Nature 417, 515–522.PubMedCrossRefGoogle Scholar
  25. Jiang, Y., Lee, A., Chen, J., Ruta, V., Cadene, M., Chait, B.T. et al. (2003). X-ray structure of a voltage-dependent K+ channel. Nature 423, 33–41.PubMedCrossRefGoogle Scholar
  26. Kagan, A., Melman, Y.F., Krumerman, A., and McDonald, T.V. (2002). 14-3-3 amplifies and prolongs adrenergic stimulation of HERG K+ channel activity. EMBO J. 21, 1889–1898.PubMedCrossRefGoogle Scholar
  27. Kang, M., Moroni, A., Gazzarrini, S., DiFrancesco, D., Thiel, G., Severino, M., Van Etten, J.L. (2004). Small potassium ion channel proteins encoded by chlorella viruses. PNAS 101, 5318–5324.PubMedCrossRefGoogle Scholar
  28. Kelly, M.L., Cook, J.A., Brown-Augsburger, P., Heinz, B.A., Smith, M.C., and Pinto, L.H. (2003). Demonstrating the intrinsic ion channel activity of virally encoded proteins. FEBS Lett. (in press).Google Scholar
  29. Kuo, A., Gulbis, J.M., Antcliff, J.F., Rahman, T., Lowe, E., Zimmer, J. et al. (2003). Crystal structure of the potassium channel KirBac1.1 in the closed state. Science 300, 1922–1926.PubMedCrossRefGoogle Scholar
  30. Li, J., Xu, Q., Cortes, D.M., Perozo, E., Laskey, A., and Karlin, A. (2002). Reactions of cysteins substituted in the amphipathic N-terminus tail of a bacterial potassium channel with hydrophilic and hydrophobic maleimides. Proc. Natl. Sci. USA 99, 11605–11610.CrossRefGoogle Scholar
  31. MacKinnon, R., Cohen, S.L., Kuo, A., Lee, A., and Chait, B.T. (1998). Structural conservation in prokaryotic and eukaryotic potassium channels. Science 280, 106–109.PubMedCrossRefGoogle Scholar
  32. MacKinnon, R. and Miller, C. (1989). Mutant potassium channels with altered binding of charybdotoxin, a pore-blocking peptide inhibitor. Science 245, 1382–1385.PubMedCrossRefGoogle Scholar
  33. Martin, K. and Helenius, A. (1991). Nuclear transport of influenza virus ribonucleoproteins: The viral matrix protein (M1) promotes export and inhibits import. Cell 67, 117–130.PubMedCrossRefGoogle Scholar
  34. Mehmel, M., Rothermel, M., Meckel, T., Van J.L., Etten, Moroni, A., and Thiel, G. (2003). Possible function for virus encoded K+ channel Kcv in the replication of chlorella virus PBCV-1. FEBS Lett. 552, 7–11.PubMedCrossRefGoogle Scholar
  35. Miller, C. (2000). Ion channels: Doing hard chemistry with hard ions. Curr. Opin. Chem. Biol. 4, 148–151.PubMedCrossRefGoogle Scholar
  36. Moroni, A., Viscomi, C., Sangiorgio, V., Pagliuca, C., Meckel, T., Horvath, F. et al. (2002). The short N-terminus is required for functional expression of the virus-encoded miniature K+ channel Kcv. FEBS Lett. 530, 65–69.PubMedCrossRefGoogle Scholar
  37. Mould, J.A., Paterson, R.G., Takeda, M., Ohigashi, Y., Venkataraman, P., Lamb, R.A. et al. (2003). Influenza B virus BM2 protein has ion channel activity that conducts protons across membranes. Dev. Cell 5, 175–184.PubMedCrossRefGoogle Scholar
  38. Pinto, L.H., Holsinger, L.J., and Lamb, R.A. (1992). Influenza virus M2protein has ion channel activity. Cell 69, 517–528.PubMedCrossRefGoogle Scholar
  39. Piller, S.C., Jans, P., Gage, P.W., and Jans, D.A. (1998). Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: Implications for AIDS pathology. Proc. Natl. Acad. Sci. USA 95, 4595–4600.PubMedCrossRefGoogle Scholar
  40. Piller, S.C., Ewart, G.D., Jans, D.A., Gage, P.W., and Cox, G.B. (1999). The amino-terminal region of Vpr from human immunodeficient virus Type 1 forms ion channels and kills neurons. J. Virol. 73, 4230–4238.PubMedGoogle Scholar
  41. Plugge, B., Gazzarrini, S., Nelson, M., Cerana, R., Van Etten, J.L., Derst, C. et al. (2000). A potassium channel protein encoded by chlorella virus PBCV-1. Science 287, 1641–1644.PubMedCrossRefGoogle Scholar
  42. Schrempf, H., Schimdt, O., Kümmerlen, R., Hinnah, S., Müller, D., Betzler, M. et al. (1995). EMBO J. 114, 5170–5178.Google Scholar
  43. Skrdla, M.P., D.E. Burbank, Y. Xia, R.H. Meints, and J.L. Van Etten, (1984). Structural proteins and lipids in a virus, PBCV-1, which replicates in a chlorella-like alga. Virology 135, 308–315.PubMedCrossRefGoogle Scholar
  44. Van Etten, J.L. (2000). Phycodnaviridae. In M.H.V. Van Regenmortel, C.M. Fauquet, D.H.L. Bishop, E.B. Carstens, M.K. Estes, S.M. Lemon et al. (eds), Virus Taxonomy, Classification and Nomenclature of Viruses, 7th rep., Academic Press, San Diego: CA, pp. 183–193.Google Scholar
  45. Van Etten, J.L. (2003). Unusual life style of giant chlorella viruses. Annu. Rev. Genet. 37, 163–195.CrossRefGoogle Scholar
  46. Van Etten, J.L. and Meints, R.H. (1999). Giant viruses infecting algae. Annu. Rev. Microbiol. 53, 447–494.PubMedCrossRefGoogle Scholar
  47. Van Etten J.L., Burbank, D.E., Joshi, J., and Meints, R.H. (1984). DNA synthesis in a chlorella-like alga following infection with the virus PBCV-1. Virology 134, 443–449.CrossRefPubMedGoogle Scholar
  48. Van Etten, J.L., Burbank, D.E., Kuczmarski, D., and Meints, R.H. (1983). Virus infection of culturable Chlorella-like algae and development of a plaque assay. Science 219, 994–997.CrossRefGoogle Scholar
  49. Van Etten, J.L., Graves, M.V., Müller, D.G., Boland, W., and Delaroque, N. (2002). Phycodnaviridae-large DNA viruses. Arch. Virol. 147, 1479–1516.PubMedCrossRefGoogle Scholar
  50. Very, A.A. and Sentenac, H. (2002). Cation channels in the Arabidopsis plasma membrane. Trends Plant Sci. 7, 168–175.Google Scholar
  51. Wang, C., Takeuchi, K., Pinto, L.H., and Lamb, R.A. (1993). Ion channel activity of influenza A virus M2 protein: Characterization of the amantadine block. J. Virol. 67, 5585–5594.PubMedGoogle Scholar
  52. Watanabe, T., Watanabe, S., Ito, H., Kida, H., and Kawaoka, Y. (2001). Influenza A virus can undergo multiple cycles of replication without M2 ion channel activity. J. Virol. 75, 5656–5662.PubMedCrossRefGoogle Scholar
  53. Wei, A., Jegla, T., and Salkoff, L. (1996). Eight potassium channel families revealed by the C. elegans genome project. Neuropharmacology 37, 805–829.CrossRefGoogle Scholar
  54. Wolf, S., Maier, I., Katsaros, C., and Müller, D.G. (1998). Virus assembly in Hincksia hincksiae (Ectocarpales, Phaeophyceae). An electron and fluorescence microscopic study. Protoplasma 203, 153–167.CrossRefGoogle Scholar
  55. Yan, X., Olson, N.H., Van Etten, J.L., Bergoin, M., Rossmann, M.G., and Baker, T.S. (2000). Structure and assembly of large lipid-containing dsDNA viruses. Nat. Struct. Biol. 7, 101–103.PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic/Plenum Publishers, New York 2005

Authors and Affiliations

  • Anna Moroni
    • 1
    • 2
  • James Van Etten
    • 3
  • Gerhard Thiel
    • 4
  1. 1.Dipartimento di Biologia and CNR—IBFUnità di MilanoMilano
  2. 2.Istituto Nazionale di Fisica della MateriaUnità di Milano-UniversitàMilanoItaly
  3. 3.Department of Plant Pathology, Nebraska Center for VirologyUniversity of NebraskaLincoln
  4. 4.Institute for BotanyUniversity of Technology DarmstadtGermany

Personalised recommendations