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Is there a Place for Epinephrine in the Management of Septic Shock?

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Yearbook of Intensive Care and Emergency Medicine 2005

Part of the book series: EN]Yearbook of Intensive Care and Emergency Medicine ((volume 2005))

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References

  1. Hollenberg SM, Ahrens TS, Annane D, et al (2004) Practice parameters for hemodynamic support of sepsis in adult patients: 2004 update. Crit Care Med 32:1928–1948

    Article  PubMed  Google Scholar 

  2. Rudis MI, Basha MA, Zarowitz BJ (1996) Is it time to reposition vasopressors and inotropes in sepsis? Crit Care Med 24:525–537

    Article  PubMed  Google Scholar 

  3. Bearn AG, Billing B, Sherlock S (1951) The effect of adrenaline and noradrenaline on hepatic blood flow and splanchnic carbohydrate metabolism in man. J Physiol 115:430–441

    PubMed  Google Scholar 

  4. Eusinger H, Weichel T, Lindner KH, Grunert A, Georgieff M (1995) Are the effects of noradrenaline, adrenaline and dopamine infusions on VO2 and metabolism transient? Intensive Care Med 21:50–56

    PubMed  Google Scholar 

  5. Wilson W, Lipman J, Scribante J, et al (1992) Septic shock: does adrenaline have a role as a first-line inotropic agent? Anaesth Intensive Care 20:470–474

    PubMed  Google Scholar 

  6. Moran JL, O'Fathartaigh MS, Peisach AR, Chapman MJ, Leppard P (1993) Epinephrine as an inotropic agent in septic shock: a dose-profile analysis. Crit Care Med 21:70–77

    Google Scholar 

  7. Le Tulzo Y, Seguin P, Gacouin A, et al (1997) Effects of epinephrine on right ventricular function in patients with severe septic shock and right ventricular failure: a preliminary descriptive study. Intensive Care Med 23:664–670

    Article  PubMed  Google Scholar 

  8. Levy B, Bollaert PE, Charpentier C, et al (1997) Comparison of norepinephrine and dobutamine to epinephrine for hemodynamics, lactate metabolism, and gastric tonometric variables in septic shock: a prospective, randomized study. Intensive Care Med 23:282–287

    Article  PubMed  Google Scholar 

  9. Levy B, Mansart A, Bollaert PE, Franck P, Mallie JP (2003) Effects of epinephrine and norepinephrine on hemodynamics, oxidative metabolism, and organ energetics in endotoxemic rats. Intensive Care Med 29:292–300

    PubMed  Google Scholar 

  10. James JH, Luchette FA, McCarter FD, Fischer JE (1999) Lactate is an unreliable indicator of tissue hypoxia in injury or sepsis. Lancet 354:505–508

    Article  PubMed  Google Scholar 

  11. Levy B, Gawalkiewicz P, Vallet B, Briancon S, Nace L, Bollaert PE (2003) Gastric capnometry with air-automated tonometry predicts outcome in critically ill patients. Crit Care Med 31:474–480

    Article  PubMed  Google Scholar 

  12. Chapman MV, Mythen MG, Webb AR, Vincent JL (2000) Report from the meeting: Gastrointestinal Tonometry: State of the Art. 22nd–23rd May 1998, London, UK. Intensive Care Med 26:613–622

    Article  PubMed  Google Scholar 

  13. Duranteau J, Sitbon P, Teboul JL, et al (1999) Effects of epinephrine, norepinephrine, or the combination of norepinephrine and dobutamine on gastric mucosa in septic shock. Crit Care Med 27:893–900

    Article  PubMed  Google Scholar 

  14. De Backer D, Creteur J, Silva E, Vincent JL (2003) Effects of dopamine, norepinephrine, and epinephrine on the splanchnic circulation in septic shock: which is best? Crit Care Med 31:1659–1667

    Article  PubMed  Google Scholar 

  15. Meier-Hellmann A, Reinhart K, Bredle DL, Specht M, Spies CD, Hannemann L (1997) Epinephrine impairs splanchnic perfusion in septic shock. Crit Care Med 25:399–404

    Article  PubMed  Google Scholar 

  16. Levy B, Bollaert PE, Lucchelli JP, Sadoune LO, Nace L, Larcan A (1997) Dobutamine improves the adequacy of gastric mucosal perfusion in epinephrine-treated septic shock. Crit Care Med 25:1649–1654

    Article  PubMed  Google Scholar 

  17. Seguin P, Bellissant E, Le Tulzo Y, et al (2002) Effects of epinephrine compared with the combination of dobutamine and norepinephrine on gastric perfusion in septic shock. Clin Pharmacol Ther 71:381–388

    PubMed  Google Scholar 

  18. Mullner M, Urbanek B, Havel C, Losert H, Waechter F, Gamper G (2004) Vasopressors for shock. Cochrane Database Syst Rev CD003709

    Google Scholar 

  19. Levy B (2003) Epinephrine in septic shock: Dr. Jekyll or Mr. Hyde? Crit Care Med 31:1866–1867

    Article  PubMed  Google Scholar 

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Authors
  1. B. Levy
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  2. S. Gibot
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  3. P.E. Bollaert
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Free University of Brussels, Route de Lennik 808, B-1070, Brussels, Belgium

    Jean-Louis Vincent (Head) (Head)

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© 2005 Springer-Verlag Berlin Heidelberg

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Levy, B., Gibot, S., Bollaert, P. (2005). Is there a Place for Epinephrine in the Management of Septic Shock?. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine 2005. EN]Yearbook of Intensive Care and Emergency Medicine, vol 2005. Springer, New York, NY. https://doi.org/10.1007/0-387-26272-5_22

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  • DOI: https://doi.org/10.1007/0-387-26272-5_22

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-3-540-23476-0

  • Online ISBN: 978-0-387-26272-7

  • eBook Packages: MedicineMedicine (R0)

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