Advertisement

Cell Fate and Polarity

Part of the Biological and Medical Physics, Biomedical Engineering book series (BIOMEDICAL)

Keywords

Nurse Cell Notch Receptor Cell Fate Decision Planar Cell Polarity Morphogen Gradient 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References and Further Reading

Notch Signaling

  1. Artavanis-Tsakonas S, Rand MD, and Lake RJ [1999]. Notch signaling: Cell fate control and signal integration in development. Science, 284: 770–776.CrossRefADSGoogle Scholar
  2. Lai EC [2002]. Keeping a good pathway down: Transcriptional repression of Notch pathway target genes by CSL proteins. EMBO Rep., 3: 840–845.CrossRefGoogle Scholar
  3. Milner LA, and Bigas A [1999]. Notch as a mediator of cell fate determination in hematopoiesis: Evidence and speculation. Blood, 93: 2431–2448.Google Scholar
  4. Schroeter EH, Kisslinger JA, and Kopan R [1998]. Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain. Nature, 393: 382–386.CrossRefADSGoogle Scholar
  5. Struhl G, and Adachi A [1998]. Nuclear access and action of Notch in vivo. Cell, 93: 649–660.CrossRefGoogle Scholar

Presenilins and Matrix Metalloproteinases

  1. De Strooper B [2003]. Aph-1, Pen-2, and Nicastrin with Presenilin generate an active γ-secretase complex. Neuron, 38: 9–12.CrossRefGoogle Scholar
  2. De Strooper B, and Annaert W [2000]. Proteolytic processing and cell biological function of the amyloid precursor protein. J. Cell Sci., 113: 1857–1870.Google Scholar
  3. Fortini ME [2001]. Notch and Presenilin: A proteolytic mechanism emerges. Curr Opin. Cell Biol., 13: 627–634.CrossRefGoogle Scholar
  4. Schlondorff J, and Blobel CP [1999]. Metalloprotease-disintegrins: Modular proteins capable of promoting cell-cell interactions and triggering signals by proteinectodomain shedding. J. Cell Sci., 112: 3603–3617.Google Scholar
  5. Vu TH, and Werb Z [2000]. Matrix metalloproteinases: Effectors of development and normal physiology. Genes Dev., 14: 2123–2133.CrossRefGoogle Scholar

TGF-β Signaling (Receptor Serine/Threonine Kinase Pathway)

  1. Moustakas A, Souchelnytskyi S, and Heldin CH [2001]. Smad regulation in TGF-β signal transduction. J. Cell Sci., 114: 4359–4369.Google Scholar
  2. Qin BY, et al. [2002]. Smad3 allostery links TGF-β receptor kinase activation to transcriptional control. Genes Dev., 16: 1950–1963.CrossRefGoogle Scholar
  3. Shi YG, and Massagué J [2003]. Mechanism of TGF-β signaling from cell membrane to the nucleus. Cell, 113: 685–700.CrossRefGoogle Scholar
  4. Ten Dijke P, et al. [2002]. Regulation of cell proliferation by Smad proteins. J. Cell Physiol., 191: 1–16.CrossRefGoogle Scholar
  5. Ten Dijke P, Miyazono K, and Heldin CH [2000]. Signaling inputs converge on nuclear effectors in TGF-β signaling. Trends Biochem. Sci., 25: 64–70.CrossRefGoogle Scholar

Wnt Signaling Pathway

  1. Cardigan KM, and Nusse R [1997]. Wnt signaling: A common theme in animal development. Genes Dev., 11: 3286–3305.CrossRefGoogle Scholar
  2. Dale TC [1998]. Signal transduction by the Wnt family of ligands. Biochem. J., 329: 209–223.Google Scholar
  3. Kalderon D [2002]. Similarities between the Hedgehog and Wnt signaling pathways. Trends Cell Biol., 12: 523–531.CrossRefGoogle Scholar
  4. Ma D, et al. [2003]. Fidelity in planar cell polarity signaling. Nature, 421: 543–547.CrossRefADSGoogle Scholar
  5. Mlodzik M [1999]. Planar polarity in the Drosophila eye: A multifaceted view of signaling specificity and cross-talk. EMBO J., 18: 6873–6879.CrossRefGoogle Scholar
  6. Moon RT, Brown JD, and Torres M [1997]. Wnts modulate cell fate and behavior during vertebrate development. Trends Genet., 13: 157–162.CrossRefGoogle Scholar
  7. Wallingford JB, Fraser SE, and Harland RM [2002]. Convergent extension: The molecular control of polarized cell movement during embryonic development. Dev. Cell, 2: 695–706.CrossRefGoogle Scholar

Hedgehog Signaling

  1. Collins RT, and Cohen SM [2003]. The secret life of Smoothened. Dev. Cell, 5:823–824.CrossRefGoogle Scholar
  2. Hammerschmidt M, Brook A, and McMahon AP [1997]. The world according to Hedgehog. Trends Genet., 13: 14–21.CrossRefGoogle Scholar
  3. Ingham PW [1998]. Transducing Hedgehog: The story so far. EMBO J., 17: 3505–3511.CrossRefGoogle Scholar
  4. Ingham PW, and McMahon AP [2001]. Hedgehog signaling in animal development: Paradigms and principles. Genes Dev., 15: 3059–3087.CrossRefGoogle Scholar
  5. Taipale J, et al. [2002]. Patched acts catalytically to suppress the activity of Smoothened. Nature, 418: 892–897.CrossRefADSGoogle Scholar

Morphogens

  1. Lawrence PA, and Struhl G [1996]. Morphogens, compartments, and pattern: Lessons from Drosophila? Cell, 85: 951–961.CrossRefGoogle Scholar
  2. Teleman AA, Strigini M, and Cohen SM [2001]. Shaping morphogen gradients. Cell, 105: 559–562.CrossRefGoogle Scholar

Vertebrate Organizers and Body Plan

  1. Lemaire P, and Kodjabachian L [1996]. The vertebrate organizer: Structure and molecules. Trends Genet., 12: 525–531.CrossRefGoogle Scholar
  2. Schier AF, and Shen MM [2000]. Nodal signaling in vertebrate development. Nature, 403: 385–389.CrossRefADSGoogle Scholar
  3. Sokol SY [1999]. Wnt signaling and dorsal-ventral axis specification in vertebrates. Curr. Opin. Genet. Dev., 9: 405–410.CrossRefGoogle Scholar

Feedback Loops in Development

  1. Eldar A, et al. [2002]. Robustness of the Bmp morphogen gradient in Drosophila embryonic patterning. Nature, 419: 304–308.CrossRefADSGoogle Scholar
  2. Freeman M [2000]. Feedback control of intercellular signalling in development. Nature, 408: 313–319.CrossRefADSGoogle Scholar

Selector Genes, Gene Regulatory Networks, and the Segmentation Clock

  1. Curtiss J, Halder G, and Mlodzik [2002]. Selector and signaling molecules cooperate in organ patterning. Nature Cell Biol., 4: E48–E51.CrossRefGoogle Scholar
  2. Davidson EH, et al. [2002]. A genomic regulatory network for development. Science, 295: 1669–1678.CrossRefADSGoogle Scholar
  3. Guss KA, et al. [2001]. Control of a genetic regulatory network by a selector gene. Science, 292: 1164–1167.CrossRefADSGoogle Scholar
  4. Hirata H, et al. [2002]. Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science, 298: 840–843.CrossRefADSGoogle Scholar
  5. Saga Y, and Takeda H [2001]. The making of the somite: Molecular events in vertebrate segmentation. Nature Rev. Genet., 2: 835–845.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2005

Personalised recommendations