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Closing the Loop: Stimulation Feedback Systems for Embodied MEA Cultures

  • Steve M. Potter
  • Daniel A. Wagenaar
  • Thomas B. DeMarse
Chapter

9.7 Conclusion

By combining MEA electrophysiology with long-term time-lapse imaging, it is possible to make correlations between changes in network function and changes in neuronal morphology. By re-embodying dissociated cultured networks, network function can be mapped onto behavior, and in vitro research can now make use of a new kind of behavioral studies that include detailed (submicron) imaging not possible in vivo. By closing the sensory-motor loop around MEA cultures, they are more likely to shed light on the mechanisms of learning, memory, and information processing in animals.

Keywords

Stimulation System Stimulus Artifact Raster Plot Motor Loop Multi Channel System 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  • Steve M. Potter
    • 1
  • Daniel A. Wagenaar
    • 2
  • Thomas B. DeMarse
    • 3
  1. 1.Department of Biomedical Engineering, Georgia Institute of TechnologyEmory Univrsity School of MedicineAtlantaUSA
  2. 2.Department of PhysicsCalifornia Institute of TechnologyPasadena
  3. 3.Department of Biomedical EngineeringUniversity of FloridaGainesvilleUSA

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