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Hormonal and Gender Influences on Experimental Autoimmune Encephalomyelitis

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Book cover Experimental Models of Multiple Sclerosis

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Abstract

This chapter highlights the important interactions between the CNS, the endocrine system and the immune system that influence the course of EAE. In particular, we focus on the bi-directional relationship between the hypothalamic-pituitary-adrenal (HPA) axis and EAE, and the influences of gender and sex hormones on EAE.

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Author information

Authors and Affiliations

  1. Division of Clinical Neurology, University of Nottingham, UK

    Christopher Gilmore & Cris S Constantinescu

  2. Department of Molecular Virology, Immunology and Medical Genetics, Ohio State University, Columbus, OH, USA

    Caroline C Whitacre

Authors
  1. Christopher Gilmore
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  2. Cris S Constantinescu
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  3. Caroline C Whitacre
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Editor information

Editors and Affiliations

  1. Weill Medical College of Cornell University, New York

    Ehud Lavi

  2. Queen’s Medical Centre, University Hospital, Nottingham, UK

    Cris S. Constantinescu

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Gilmore, C., Constantinescu, C.S., Whitacre, C.C. (2005). Hormonal and Gender Influences on Experimental Autoimmune Encephalomyelitis. In: Lavi, E., Constantinescu, C.S. (eds) Experimental Models of Multiple Sclerosis. Springer, Boston, MA. https://doi.org/10.1007/0-387-25518-4_26

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