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B Cells and Antibodies in Experimental Autoimmune Encephalomyelitis

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Experimental Models of Multiple Sclerosis

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Abstract

EAE is a T cell mediated disease, but increasing evidence shows an important role for B cells and antibodies in its pathogenesis. This also reflects a role for humoral factors in the pathogenesis of multiple sclerosis. The main functions of B cells and antibodies in EAE are discussed.

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Authors and Affiliations

  1. Division of Clinical Neurology, University of Nottingham, UK

    Xia Lin & Cris S Constantinescu

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  1. Xia Lin
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  2. Cris S Constantinescu
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Editors and Affiliations

  1. Weill Medical College of Cornell University, New York

    Ehud Lavi

  2. Queen’s Medical Centre, University Hospital, Nottingham, UK

    Cris S. Constantinescu

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Lin, X., Constantinescu, C.S. (2005). B Cells and Antibodies in Experimental Autoimmune Encephalomyelitis. In: Lavi, E., Constantinescu, C.S. (eds) Experimental Models of Multiple Sclerosis. Springer, Boston, MA. https://doi.org/10.1007/0-387-25518-4_13

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