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Therapeutic Hypothermia pp 211–233Cite as

Cooling Methods

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Part of the book series: Molecular and Cellular Biology of Critical Care Medicine ((MCCM,volume 4))

Abstract

Laboratory studies of therapeutic hypothermia have utilized animals that are much smaller than the average-sized human, making rapid cooling feasible. Cooling techniques can be very invasive without concern about the long-term risks. In addition, cooling is often started either before or early during the insult. For therapeutic hypothermia to be taken to clinical trials and, further, to become part of standard clinical practice, novel cooling techniques will be needed. The optimal technique for total body cooling should be easily applied, should cool the entire organism rapidly, and should carry little risk. Ideally, the technique should be applicable by lay people or physician extenders, preferably even in the field. In addition, techniques for selective brain cooling may provide the same benefits without the possible systemic side effects.

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Author information

Authors and Affiliations

  1. Büro für Thermophysiologie, Pohlheim, Germany

    Gernot Kuhnen PhD

  2. Institute of Medical Biology, University of Southern Denmark, Odense, Denmark

    Niels Einer-Jensen DVM

  3. Safar Center for Resuscitation Research, University of Pittsburgh, Pittsburgh, PA

    Samuel A. Tisherman MD

Authors
  1. Gernot Kuhnen PhD
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  2. Niels Einer-Jensen DVM
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  3. Samuel A. Tisherman MD
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Editor information

Editors and Affiliations

  1. Department of Critical Care, University of Pittsburgh, Pittsburgh, PA, 15213, USA

    Samuel A. Tisherman MD

  2. Emergency Medicine, Medical University of Vienna, 1090, Vienna, Austria

    Fritz Sterz MD

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Kuhnen, G., Einer-Jensen, N., Tisherman, S.A. (2005). Cooling Methods. In: Tisherman, S.A., Sterz, F. (eds) Therapeutic Hypothermia. Molecular and Cellular Biology of Critical Care Medicine, vol 4. Springer, Boston, MA. https://doi.org/10.1007/0-387-25403-X_14

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  • DOI: https://doi.org/10.1007/0-387-25403-X_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-25402-9

  • Online ISBN: 978-0-387-25403-6

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