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Leptomeningeal Metastases pp 71–85Cite as

Leptomeningeal Metastasis of Primary Central Nervous System (CNS) Neoplasms

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Part of the book series: Cancer Treatment and Research ((CTAR,volume 125))

Abstract

Leptomeningeal dissemination of primary CNS tumors varies widely by histologic subtype. In certain tumors including medulloblastoma, ependymoma, germ cell tumors, and primary CNS lymphoma, seeding of the cerebrospinal fluid space is a critical factor in determining stage, prognosis and appropriate therapy. Other tumor types, such as glioma, may have radiographic evidence of leptomeningeal metastases without clear impact on prognosis or therapy.

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Authors and Affiliations

  1. The University of Illinois at Chicago, Chicago, Illinois

    Herbert H. Engelhard M.D., Ph.D. & Luke A. Corsten M.D.

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  1. Herbert H. Engelhard M.D., Ph.D.
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  2. Luke A. Corsten M.D.
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Editors and Affiliations

  1. Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10021

    Lauren E. Abrey M.D.

  2. Department of Neurology, University of Southern California, Norris Comprehensive Cancer Center and Hospital, Los Angeles, CA, 90033

    Marc C. Chamberlain M.D.

  3. Departments of Neurosurgery, Bioengineering & Molecular Genetics, University of Illinois at Chicago, Chicago, IL, 60612

    Herbert H. Engelhard M.D., PhD.

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Engelhard, H.H., Corsten, L.A. (2005). Leptomeningeal Metastasis of Primary Central Nervous System (CNS) Neoplasms. In: Abrey, L.E., Chamberlain, M.C., Engelhard, H.H. (eds) Leptomeningeal Metastases. Cancer Treatment and Research, vol 125. Springer, Boston, MA. https://doi.org/10.1007/0-387-24199-X_5

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  • DOI: https://doi.org/10.1007/0-387-24199-X_5

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