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Neuroendocrine Correlates of Sleep/Wakefulness pp 41–58Cite as

The Neuroendocrine Loop Model Revisited: Is It Valid or Even Relevant?

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Abstract

Biological rhythms and the biological clocks that control them are fundamental properties of most living organisms, ranging from several forms of bacteria to multicellular plants and animals. These properties share many formal and biochemical properties, and affect all aspects of physiological function, ranging from control of transcription to metabolism to cell cycle to behavior. Because these rhythms are expressed similarly in single-celled and multi-cellular organisms, and because clock function pervades all levels of biological organization, many authors have suggested that biological clocks are properties of all cells.1

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Authors and Affiliations

  1. Department of Biology, Texas A&M University, College Station, TX

    Vincent M. Cassone

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  1. Vincent M. Cassone
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  1. Department of Physiology Faculty of Medicine, University of Buenos Aires, Argentina, Buenos Aires, 1121

    Daniel P. Cardinali

  2. SUNY Downstate Medical Center, Brooklyn, 11203, New York, USA

    S. R. Pandi-Perumal

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Cassone, V.M. (2006). The Neuroendocrine Loop Model Revisited: Is It Valid or Even Relevant?. In: Cardinali, D.P., Pandi-Perumal, S.R. (eds) Neuroendocrine Correlates of Sleep/Wakefulness. Springer, Boston, MA. https://doi.org/10.1007/0-387-23692-9_3

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